Endobronchial Ultrasound (EBUS) – Update 2017

Abstract

Endobronchial ultrasound (EBUS) has revolutionized the diagnosis of lung cancer over the last decade. This minimally invasive diagnostic method has also become increasingly important in the case of other diseases such as sarcoidosis, thereby helping to avoid unnecessary diagnostic interventions. This review article provides an update regarding EBUS and discusses current and future developments of this method.

Zusammenfassung

Der endobronchiale Ultraschall (EBUS) hat im letzten Jahrzehnt die Lungenkrebsdiagnostik revolutioniert. Auch bei anderen Erkrankungen wie der Sarkoidose hat der Stellenwert dieses minimalinvasiven diagnostischen Verfahrens erheblich zugenommen und somit geholfen, unnötige diagnostische Operationen zu vermeiden. Dieser Übersichtsartikel stellt ein Update zum EBUS dar und erläutert die aktuellen und zukünftigen Entwicklungen dieses Verfahrens.

• Literatur

• 1 Nakajima T, Yasufuku K, Fujiwara T. et al. Endobronchial Ultrasound-Guided Transbronchial Needle Aspiration for the Diagnosis of Intrapulmonary Lesions. J Thorac Oncol 2008; 3: 985-988
• 2 Navani N, Nankivell M, Woolhouse I. et al. Endobronchial Ultrasound-Guided Transbronchial Needle Aspiration for the Diagnosis of Intrathoracic Lymphadenopathy in Patients with Extrathoracic Malignancy – A Multicenter Study. J Thorac Oncol 2011; 6: 1505-1509
• 3 Navani N, Nankivell M, Lawrence DR. et al. Lung cancer diagnosis and staging with endobronchial ultrasound-guided transbronchial needle aspiration compared with conventional approaches: an open-label, pragmatic, randomised controlled trial. Lancet Respir Med 2015; 3: 282-289
• 4 Gu P, Zhao YZ, Jiang LY. et al. Endobronchial ultrasoundguided transbronchial needle aspiration for staging of lung cancer: a systematic review and meta-analysis. Eur J Cancer 2009; 45: 1389-1396
• 5 Herth FJ, Eberhardt R, Vilmann P. et al. Real-time endobronchial ultrasound guided transbronchial needle aspiration for sampling mediastinal lymph nodes. Thorax 2006; 61: 795-798
• 6 Yasufuku K, Pierre A, Darling G. et al. A prospective controlled trial of endobronchial ultrasound-guided transbronchial needle aspiration compared with mediastinoscopy for mediastinal lymph node staging of lung cancer. J Thorac Cardiovasc Surg 2011; 142: 1393-1400
• 7 Herth FJ, Eberhardt R, Krasnik M. et al. Endobronchial Ultrasound-Guided Transbronchial Needle Aspiration of Lymph Nodes in the Radiologically and Positron Emission Tomography-Normal Mediastinum in Patients With Lung Cancer. Chest 2008; 133: 887-891
• 8 Naur TMH, Konge L, Clementsen PF. Endobronchial Ultrasound-Guided Transbronchial Needle Aspiration for Staging of Patients with Non-Small Cell Lung Cancer without Mediastinal Involvement at Positron Emission Tomography-Computed Tomography. Respiration 2017; 94: 279-284
• 9 Gao SJ, Kim AW, Puchalski JT. et al. Indications for invasive mediastinal staging in patients with early non-small cell lung cancer staged with PET-CT. Lung Cancer 2017; 109: 36-41
• 10 Silvestri GA, Gonzalez AV, Jantz MA. et al. Methods for staging non-small cell lung cancer: Diagnosis and management of lung cancer, 3rd ed: American College of Chest Physicians evidence-based clinical practice guidelines. Chest 2013; 143: e211S-e250S
• 11 Hwangbo B, Lee GK, Lee HS. et al. Transbronchial and transesophageal fine-needle aspiration using an ultrasound bronchoscope in mediastinal staging of potentially operable lung cancer. Chest 2010; 138: 795-802
• 12 Xiong J, Wang R, Sun Y. Lymph node metastasis according to primary tumor location in T1 and T2 stage non-small cell lung cancer patients. Thorac Cancer 2016; 26: 304-309
• 13 Vilmann P, Clementsen PF, Colella S. Combined endobronchial and esophageal endosonography for the diagnosis and staging of lung cancer: European Society of Gastrointestinal Endoscopy (ESGE) Guideline, in cooperation with the European Respiratory Society (ERS) and the European Society of Thoracic Surgeons (ESTS). Endoscopy 2015; 47: 545-559
• 14 Patil R, Ona MA, Papafragkakis C. et al. Endoscopic ultrasound-guided fine-needle aspiration in the diagnosis of adrenal lesions. Ann Gastroenterol 2016; 29: 307-311
• 15 Crombag LM, Annema JT. Left Adrenal Gland Analysis in Lung Cancer Patients Using the Endobronchial Ultrasound Scope: A Feasibility Trial. Respiration 2016; 91: 235-240
• 16 Wahidi MM, Herth F, Yasufuku K. et al. Technical Aspects of Endobronchial Ultrasound-Guided Transbronchial Needle Aspiration: CHEST Guideline and Expert Panel Report. Chest 2016; 149: 816-835
• 17 von Bartheld MB, Dekkers OM, Szlubowski A. et al. Endosonography vs Conventional for the Diagnosis of Sarcoidosis The GRANULOMA Randomized Clinical Trial. JAMA 2013; 309: 2457-2464
• 18 Navani N, Molyneaux PL, Breen RA. et al. Utility of endobronchial ultrasound-guided transbronchial needle aspiration in patients with tuberculous intrathoracic lymphadenopathy: a multicentre study. Thorax 2011; 66: 889-893
• 19 Schaberg T, Bauer T, Brinkmann F. et al. S2k-Leitlinie: Tuberkulose im Erwachsenenalter. Pneumologie 2017; 71: 325-397
• 20 Kennedy MP, Jimenez CA, Bruzzi JF. et al. Endobronchial ultrasound-guided transbronchial needle aspiration in the diagnosis of lymphoma. Thorax 2008; 63: 360-365
• 21 Moonim MT, Breen R, Fields PA. et al. Diagnosis and subtyping of de novo and relapsed mediastinal lymphomas by endobronchial ultrasound needle aspiration. Am J Respir Crit Care Med 2013; 188: 1216-1223
• 22 Wang L, Wu W, Hu Y. et al. Sonographic Features of Endobronchial Ultrasonography Predict Intrathoracic Lymph Node Metastasis in Lung Cancer Patients. Ann Thorac Surg 2015; 100: 1203-1209
• 23 Sun J, Zheng X, Mao X. et al. Endobronchial Ultrasound Elastography for Evaluation of Intrathoracic Lymph Nodes: A Pilot Study. Respiration 2017; 93: 327-338
• 24 Nakajima T, Yasufuku K, Takahashi R. et al. Comparison of 21-gauge and 22-gauge aspiration needle during endobronchial ultrasound-guided transbronchial needle aspiration. Respirology 2011; 16: 90-94
• 25 Oki M, Saka H, Kitagawa C. et al. Rapid on-site cytologic evaluation during endobronchial ultrasound-guided transbronchial needle aspiration for diagnosing lung cancer: a randomized study. Respiration 2013; 85: 486-492
• 26 Oezkan F, Khan A, Zarogoulidis P. et al. Efficient utilization of EBUS-TBNA samples for both diagnosis and molecular analyses. Onco Targets Ther 2014; 7: 2061-2065
• 27 Giesa C, Heining L, Hecker E. et al. Severe Complications of Ultrasound Guided Transbronchial Needle Aspiration-A Case Series and Review of the Literature. Pneumologie 2016; 70: 23-27
• 28 von Bartheld MB, van Breda A, Annema JT. Complication Rate of Endosonography (Endobronchial and Endoscopic Ultrasound): A Systematic Review. Respiration 2014; 87: 343-351
• 29 Izumo T, Sasada S, Chavez C. et al. Radial endobronchial ultrasound images for ground-glass opacity pulmonary lesions. Eur Respir J 2015; 45: 1661-1668
• 30 Ali MS, Trick W, Mba BI. et al. Radial endobronchial ultrasound for the diagnosis of peripheral pulmonary lesions: A systematic review and meta-analysis. Respirology 2017; 22: 443-453
• 31 Eberhardt R, Ernst A, Herth FJ. Ultrasound-guided transbronchial biopsy of solitary pulmonary nodules less than 20 mm. Eur Respir J 2009; 34: 1284-1287
• 32 Yasufuku K. Early diagnosis of lung cancer. Clin Chest Med 2010; 31: 39-47
• 33 Gorska K, Korczynski P, Mierzejewski M. et al. Comparison of endobronchial ultrasound and high resolution computed tomography as tools for airway wall imaging in asthma and chronic obstructive pulmonary disease. Respir Med 2016; 117: 131-138