Rectal Cancer and Radiation in Colitis

Patricio B. Lynn; Catherine Cronin; Sriram Rangarajan; Maria Widmar

doi:10.1055/s-0043-1762561

Clinics in Colon and Rectal Surgery, Table of Contents

Clin Colon Rectal Surg 2024; 37(01): 030-036
DOI: 10.1055/s-0043-1762561

Review Article

Rectal Cancer and Radiation in Colitis

Patricio B. Lynn

¹Division of Colorectal Surgery, Department of General Surgery, New York Presbyterian – Weill-Cornell, New York, New York

,

Catherine Cronin

²Colorectal Surgery Service, Department of Surgical Oncology, Memorial Sloan Kettering Cancer Center, New York, New York

,

Sriram Rangarajan

²Colorectal Surgery Service, Department of Surgical Oncology, Memorial Sloan Kettering Cancer Center, New York, New York

,

Maria Widmar

²Colorectal Surgery Service, Department of Surgical Oncology, Memorial Sloan Kettering Cancer Center, New York, New York

› Author Affiliations

Abstract

Inflammatory bowel disease (IBD) is associated with an increased risk of colorectal cancer. When IBD patients develop a rectal cancer, this should be treated with the same oncological principles and guidelines as the general population. Rectal cancer treatment includes surgery, chemotherapy, and radiation therapy (RT). Many IBD patients will require a total proctocolectomy with an ileal-pouch anal anastomosis (IPAA) and others, restoration of intestinal continuity may not be feasible or advisable. The literature is scarce regarding outcomes of IPAA after RT. In the present review, we will summarize the evidence regarding RT toxicity in IBD patients and review surgical strategies and outcomes of IPAA after RT.

Keywords

inflammatory bowel disease - rectal cancer - ileal pouch-anal anastomosis - radiation therapy - functional outcomes

Full Text

References

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