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Journal of Pediatric Neurology 2024; 22(01): 077-084
DOI: 10.1055/s-0043-1768655
Case Report

Streptococcus constellatus-Induced Blindness in a 10-Year-Old Boy: A Case Report

Sixuan Wang   *
1   Department of Infectious Disease, Key Laboratory of Major Diseases in Children, Ministry of Education, Capital Medical University, National Center for Children's Health, Beijing Children's Hospital, Beijing, China
2   Research Unit of Critical Infection in Children, Chinese Academy of Medical Sciences, Beijing, China
3   Beijing Natural Science Foundation, Beijing, China
4   Respiratory Research Project of National Clinical Research Center for Respiratory Diseases, Beijing, China
,
Zhenzhen Dou   *
1   Department of Infectious Disease, Key Laboratory of Major Diseases in Children, Ministry of Education, Capital Medical University, National Center for Children's Health, Beijing Children's Hospital, Beijing, China
2   Research Unit of Critical Infection in Children, Chinese Academy of Medical Sciences, Beijing, China
3   Beijing Natural Science Foundation, Beijing, China
4   Respiratory Research Project of National Clinical Research Center for Respiratory Diseases, Beijing, China
,
Wenya Feng
1   Department of Infectious Disease, Key Laboratory of Major Diseases in Children, Ministry of Education, Capital Medical University, National Center for Children's Health, Beijing Children's Hospital, Beijing, China
2   Research Unit of Critical Infection in Children, Chinese Academy of Medical Sciences, Beijing, China
3   Beijing Natural Science Foundation, Beijing, China
4   Respiratory Research Project of National Clinical Research Center for Respiratory Diseases, Beijing, China
,
Bing Hu
1   Department of Infectious Disease, Key Laboratory of Major Diseases in Children, Ministry of Education, Capital Medical University, National Center for Children's Health, Beijing Children's Hospital, Beijing, China
2   Research Unit of Critical Infection in Children, Chinese Academy of Medical Sciences, Beijing, China
3   Beijing Natural Science Foundation, Beijing, China
4   Respiratory Research Project of National Clinical Research Center for Respiratory Diseases, Beijing, China
,
Yanhui Cui
5   Department of Ophthalmology, National Center for Children's Health, Capital Medical University, Beijing Children's Hospital, Beijing, China
,
Xiaojian Yang
6   Department of Otolaryngology, Head and Neck Surgery, National Center for Children's Health, Capital Medical University, Beijing Children's Hospital, Beijing, China
,
Li Li
5   Department of Ophthalmology, National Center for Children's Health, Capital Medical University, Beijing Children's Hospital, Beijing, China
,
Wentong Ge
6   Department of Otolaryngology, Head and Neck Surgery, National Center for Children's Health, Capital Medical University, Beijing Children's Hospital, Beijing, China
,
Gang Liu
1   Department of Infectious Disease, Key Laboratory of Major Diseases in Children, Ministry of Education, Capital Medical University, National Center for Children's Health, Beijing Children's Hospital, Beijing, China
2   Research Unit of Critical Infection in Children, Chinese Academy of Medical Sciences, Beijing, China
3   Beijing Natural Science Foundation, Beijing, China
4   Respiratory Research Project of National Clinical Research Center for Respiratory Diseases, Beijing, China
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Abstract

In this article, we report a 10-year-old boy with acute bacteremia and left eye blindness. Culture from abscess drainage was positive for Streptococcus constellatus. Infection caused by S. constellatus is rare among children, and to our knowledge, this is the first report of this pathogen causing blindness. The rapidness of progression in this case is alarming. We also summarize other cases of S. constellatus infection.

Keywords

pediatrics - Streptococcus constellatus - blindness - infection - abscess

Data Availability

The original contribution presented in the study is included in the article/supplementary material. Further inquiries can be directed to the corresponding author.


Ethical Approval

The studies involving human participants were reviewed and approved by the Ethics Committee of Beijing Children's Hospital. The patients/participants provided their written informed consent to participate in the study.


Authors' Contributions

All authors listed have made a substantial, direct, and intellectual contribution to the work, and approved it for publication.


* These two authors contributed equally to this work and should be regarded as joint first authors.




Publication History

Received: 24 October 2022

Accepted: 19 March 2023

Article published online:
13 June 2023

© 2023. Thieme. All rights reserved.

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