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Journal of Pediatric Epilepsy
DOI: 10.1055/s-0044-1788053
Case Report

New-Onset Status Epilepticus in an 11-year-old Patient with Thyroid Autoimmune Dysfunction: A Case Report of Pediatric Hashimoto Encephalopathy

Aldo F. Costa 
1   Department of Neurology, Reina Sofía Hospital, Córdoba, Spain
,
Joaquín A. Fernández-Ramos
2   Department of Paediatrics, Paediatric Neurology Unit, Reina Sofía Hospital, Córdoba, Spain
3   Pediatric Metabolism Research Group, Instituto Maimónides de Investigación Biomédica de Córdoba (IMIBIC), Córdoba, Spain
4   Clinical Research Group, Centro de Investigación Biomédica en Red de Enfermedades Raras (CIBERER), Valencia, Spain
5   Department of Medical and Surgical Sciences, University of Córdoba, Córdoba, Spain
,
Cristina Cazorla
6   Department of Neurophysiology, Reina Sofía Hospital, Córdoba, Spain
,
Eduardo López-Laso
2   Department of Paediatrics, Paediatric Neurology Unit, Reina Sofía Hospital, Córdoba, Spain
3   Pediatric Metabolism Research Group, Instituto Maimónides de Investigación Biomédica de Córdoba (IMIBIC), Córdoba, Spain
4   Clinical Research Group, Centro de Investigación Biomédica en Red de Enfermedades Raras (CIBERER), Valencia, Spain
5   Department of Medical and Surgical Sciences, University of Córdoba, Córdoba, Spain
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Abstract

Hashimoto encephalopathy (HE) is a neuropsychiatric syndrome associated with positive thyroid antibodies (Ab). Its pathophysiology is still in debate and pediatric cases are considered rare. We present a case of an 11-year-old girl with new-onset refractory status epilepticus (NORSE) who presented a good initial response to corticosteroids but then required a second line of treatment with mycophenolate. In children presenting with NORSE of suspected autoimmune origin and no identification of autoimmune encephalitis traditional Ab, HE must be considered.

Keywords

Hashimoto encephalopathy - thyroid dysfunction - status epilepticus


Publication History

Received: 24 April 2024

Accepted: 14 June 2024

Article published online:
08 July 2024

© 2024. Thieme. All rights reserved.

Georg Thieme Verlag KG
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