Subscribe to RSS
DOI: 10.1055/s-0044-1790282
Compartment Syndrome in Association with Tibial Plateau Fracture: Standardized Protocols Ensure Optimal Outcomes

Abstract
The purpose of this study was to report on the treatment, results, and longer-term outcomes of patients who sustained a tibial plateau fracture with an associated leg compartment syndrome (CS). A total of 766 patients who sustained 766 tibial plateau fractures met inclusion criteria. Fourteen patients (1.8%) were diagnosed with CS in association with a tibial plateau fracture during their initial hospitalization, 13 at the time of presentation and 1 delayed. The treatment protocol consisted of initial external fixation and fasciotomy, followed by irrigation and debridement, and eventual closure. Fasciotomy cases included 2/14 (14.3%) single incision approaches and 12/14 (85.7%) dual incision approaches. Operative treatment of the tibial plateau fracture was performed at the time of final closure or once soft tissues were permitted. One case of CS that developed following definitive fixation was treated with fasciotomy and delayed primary closure after initial stabilization. Ten (71.4%) were available at 1-year follow-up. We compared these 10 cases to the patients with operative tibial plateau fractures without CS to assess for surgical, radiographic, clinical, and functional outcomes. We used a propensity match based on age, body mass index, sex, Charleson comorbidity index, and fracture type to reduce the presence of confounding biases. Standard statistical methods were employed. Those in the CS cohort were younger males (p < 0.05). At latest follow-up, function did not differ between those in the CS group compared with the non-CS cohort (p > 0.05). Clinically, knee flexion (130.7 vs. 126; p = 0.548), residual depression (0.5 vs. 0.2; p = 0.365), knee alignment (87.7 vs. 88.3; p = 0.470), and visual analog scale pain scores (3.0 vs. 2.4; p = 0.763) did not differ between the cohorts. Although infection was higher in the CS cohort, the overall complication rates did not differ between the CS patients and non-CS cohort (p > 0.05). Early identification and standardized treatment protocols for the management of CS that develops in association with a tibial plateau fracture lead to outcome scores that were not significantly different from patients who did not develop CS.
Authors' Contribution
All authors contributed significantly to the study's design, data acquisition, and analysis and interpretation of data. All authors were actively involved in the drafting and critical revision of the manuscript.
Publication History
Received: 09 May 2024
Accepted: 13 August 2024
Article published online:
09 September 2024
© 2024. Thieme. All rights reserved.
Thieme Medical Publishers, Inc.
333 Seventh Avenue, 18th Floor, New York, NY 10001, USA
-
References
- 1 Torlincasi AM, Lopez RA, Waseem M. Acute compartment syndrome. [Updated January 16, 2023]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023
- 2 Heemskerk J, Kitslaar P. Acute compartment syndrome of the lower leg: retrospective study on prevalence, technique, and outcome of fasciotomies. World J Surg 2003; 27 (06) 744-747
- 3 Shadgan B, Pereira G, Menon M, Jafari S, Darlene Reid W, O'Brien PJ. Risk factors for acute compartment syndrome of the leg associated with tibial diaphyseal fractures in adults. J Orthop Traumatol 2015; 16 (03) 185-192
- 4 Gamulin A, Lübbeke A, Belinga P. et al. Clinical and radiographic predictors of acute compartment syndrome in the treatment of tibial plateau fractures: a retrospective cohort study. BMC Musculoskelet Disord 2017; 18 (01) 307
- 5 McMillan TE, Gardner WT, Schmidt AH, Johnstone AJ. Diagnosing acute compartment syndrome-where have we got to?. Int Orthop 2019; 43 (11) 2429-2435
- 6 Swiontkowski MF, Engelberg R, Martin DP, Agel J. Short Musculoskeletal Function Assessment questionnaire: validity, reliability, and responsiveness. J Bone Joint Surg Am 1999; 81 (09) 1245-1260
- 7 Schatzker J, McBroom R, Bruce D. The tibial plateau fracture. The Toronto experience 1968–1975. Clin Orthop Relat Res 1979; (138) 94-104
- 8 Zeltser DW, Leopold SS. Classifications in brief: Schatzker classification of tibial plateau fractures. Clin Orthop Relat Res 2013; 471 (02) 371-374
- 9 Dirschl DR, Adams GL. A critical assessment of factors influencing reliability in the classification of fractures, using fractures of the tibial plafond as a model. J Orthop Trauma 1997; 11 (07) 471-476
- 10 Moore TM. Fracture–dislocation of the knee. Clin Orthop Relat Res 1981; (156) 128-140
- 11 Zhu Y, Yang G, Luo CF. et al. Computed tomography-based three-column classification in tibial plateau fractures: introduction of its utility and assessment of its reproducibility. J Trauma Acute Care Surg 2012; 73 (03) 731-737
- 12 Obana KK, Lee G, Lee LSK. Characteristics, treatments, and outcomes of tibial plateau nonunions: a systematic review. J Clin Orthop Trauma 2020; 16: 143-148
- 13 Deng X, Hu H, Ye Z, Zhu J, Zhang Y, Zhang Y. Predictors of acute compartment syndrome of the lower leg in adults following tibial plateau fractures. J Orthop Surg Res 2021; 16 (01) 502
- 14 Egol KA, Tejwani NC, Capla EL, Wolinsky PL, Koval KJ. Staged management of high-energy proximal tibia fractures (OTA types 41): the results of a prospective, standardized protocol. J Orthop Trauma 2005; 19 (07) 448-455 , discussion 456
- 15 Du W, Hu X, Shen Y, Teng X. Surgical management of acute compartment syndrome and sequential complications. BMC Musculoskelet Disord 2019; 20 (01) 98
- 16 Costa ML, Achten J, Bruce J. et al; UK WOLLF Collaboration. Effect of negative pressure wound therapy vs standard wound management on 12-month disability among adults with severe open fracture of the lower limb: the WOLLF randomized clinical trial. JAMA 2018; 319 (22) 2280-2288
- 17 Schneiderman BA, O'Toole RV. Compartment syndrome in high-energy tibial plateau fractures. Orthop Clin North Am 2022; 53 (01) 43-50
- 18 Marchand LS, Working ZM, Rane AA. et al. Compartment syndrome in tibial plateau fractures: do previously established predictors have external validity?. J Orthop Trauma 2020; 34 (05) 238-243
- 19 Thabet AM, Simson JE, Gerzina C, Dabash S, Adler A, Abdelgawad AA. The impact of acute compartment syndrome on the outcome of tibia plateau fracture. Eur J Orthop Surg Traumatol 2018; 28 (01) 85-93
- 20 Allmon C, Greenwell P, Paryavi E, Dubina A, OʼToole RV. Radiographic predictors of compartment syndrome occurring after tibial fracture. J Orthop Trauma 2016; 30 (07) 387-391
- 21 Shadgan B, Menon M, Sanders D. et al. Current thinking about acute compartment syndrome of the lower extremity. Can J Surg 2010; 53 (05) 329-334
- 22 Tamás V, Kocsor F, Gyuris P, Kovács N, Czeiter E, Büki A. The young male syndrome-an analysis of sex, age, risk taking and mortality in patients with severe traumatic brain injuries. Front Neurol 2019; 10: 366
- 23 Garner MR, Taylor SA, Gausden E, Lyden JP. Compartment syndrome: diagnosis, management, and unique concerns in the twenty-first century. HSS J 2014; 10 (02) 143-152
- 24 Mortensen SJ, Orman S, Serino J, Mohamadi A, Nazarian A, von Keudell A. Factors associated with development of traumatic acute compartment syndrome: a systematic review and meta-analysis. Arch Bone Jt Surg 2021; 9 (03) 263-271
- 25 Frink M, Klaus AK, Kuther G. et al. Long term results of compartment syndrome of the lower limb in polytraumatised patients. Injury 2007; 38 (05) 607-613
- 26 Kugelman D, Qatu A, Haglin J, Leucht P, Konda S, Egol K. Complications and unplanned outcomes following operative treatment of tibial plateau fractures. Injury 2017; 48 (10) 2221-2229
- 27 Frink M, Hildebrand F, Krettek C, Brand J, Hankemeier S. Compartment syndrome of the lower leg and foot. Clin Orthop Relat Res 2010; 468 (04) 940-950
- 28 Cone J, Inaba K. Lower extremity compartment syndrome. Trauma Surg Acute Care Open 2017; 2 (01) e000094
- 29 Verwiebe EG, Kanlic EM, Saller J, Abdelgawad A. Thigh compartment syndrome, presentation and complications. Bosn J Basic Med Sci 2009; 9 Suppl 1 (Suppl. 01) S28-S33
- 30 Dubina AG, Morcos G, O'Hara NN. et al. Is the timing of fixation associated with fracture-related infection among tibial plateau fracture patients with compartment syndrome? A multicenter retrospective cohort study of 729 patients. Injury 2022; 53 (11) 3814-3819
- 31 Henkelmann R, Glaab R, Mende M. et al; Committee TRAUMA of the AGA-Society for Arthroscopy and Joint Surgery. Impact of surgical site infection on patients' outcome after fixation of tibial plateau fractures: a retrospective multicenter study. BMC Musculoskelet Disord 2021; 22 (01) 531
- 32 Blair JA, Stoops TK, Doarn MC. et al. Infection and nonunion after fasciotomy for compartment syndrome associated with tibia fractures: a matched cohort comparison. J Orthop Trauma 2016; 30 (07) 392-396
- 33 Haller JM, Holt D, Rothberg DL, Kubiak EN, Higgins TF. Does early versus delayed spanning external fixation impact complication rates for high-energy tibial plateau and plafond fractures?. Clin Orthop Relat Res 2016; 474 (06) 1436-1444
- 34 Reverte MM, Dimitriou R, Kanakaris NK, Giannoudis PV. What is the effect of compartment syndrome and fasciotomies on fracture healing in tibial fractures?. Injury 2011; 42 (12) 1402-1407
- 35 Merchan N, Ingalls B, Garcia J. et al. Factors associated with surgical site infections after fasciotomy in patients with compartment syndrome. J Am Acad Orthop Surg Glob Res Rev 2022; 6 (02) e22.00002
- 36 Tomlinson RE, Silva MJ. Skeletal blood flow in bone repair and maintenance. Bone Res 2013; 1 (04) 311-322