Is Clozapine Useful in Schizophrenic Patients with Concomitant Chronic Inflammatory Disease?

References

• 1 Atkin K, Kendall F, Gould D, Freeman H, Liberman J, O'Sullivan D. Neutropenia and agranulocytosis in patients receiving clozapine in the UK and Ireland.  BJP. 1996;  169 483-488
• 2 Hummer M, Kurz M, Barnas C, Fleischhacker W W. Transient neutropenia induced by clozapine.  Psychopharm. Bull.. 1992;  28 287-290
• 3 Veys P A, Wilkes S, Shah S, Noyelle R, Hoffbrand A V. Clinical experience of clozapine-induced neutropenia in the UK. Laboratory investigation using liquid culture systems and immunofluorocytometry.  Drug Safety. 1992;  7 Suppl. 1 26-32
• 4 Lindstrom L H. The effect of long-term treatment with clozapine in schizophrenia: a retrospective study in 96 patients treated with clozapine for up to 13 years.  Acta Psych. Scand.. 1988;  77 524-529
• 5 Centorrino F, Baldessarini R J, Flood J G, Kando J C, Frankenburg F R. Relation of leukocyte counts during clozapine treatment to serum concentrations of clozapine and metabolites.  AJP. 1995;  152 610-612
• 6 Gerson S L, Arce C, Meltzer H Y. N-desmethylclozapine: a clozapine metabolite that suppresses haemopoiesis.  B. J. Haematol.. 1994;  86 555-561
• 7 Emilia G, Luppi M, Ferrari M G, Barozzi P, Marasca R, Torelli G. Hepatitis C virus-induced leuko-thrombocytopenia and haemolysis.  J. Med. Virology. 1997;  53 182-184
• 8 Pirmohamed M, Park B K. Mechanisms of clozapine-induced agranulocytosis.  CNS drugs. 1997;  7 139-158
• 9 Ahokas A, Elonen E. Circadian rhythm of white blood cells during clozapine treatment.  Psychopharmacology. 1999;  144 301-302