Proximal Aortic Dissection Late After Aortic Valve Surgery: 119 Cases of a Distinct Clinical Entity[*]
Y. von Kodolitsch1
, R. Loose4
, J. Ostermeyer2
, A. Aydin1
, D. H. Koschyk1
, A. Haverich3
, C. A. Nienaber1
, Y. von Kodolitsch1
, R. Loose4
, J. Ostermeyer2
, A. Aydin1
, D. H. Koschyk1
, A. Haverich3
, C. A. Nienaber1
1Department of Internal Medicine, Division of Cardiology at the University Hospital Eppendorf, Hamburg, 2Department of Cardiovascular Surgery, St. Georg Hospital, Hamburg, 3Department of Cardiovascular Surgery of the Hannover Medical School, Hannover, 4Department of Cardiovascular Surgery, Christian-Albrechts-University, Kiel, Germany[1]
Background: Besides systemic hypertension and Marfan syndrome, only previous aortic valve replacement (AVR) is independently associated with proximal (type A) aortic dissection. Little, however, is known to date about the characteristic features of this clinical entity. Methods: Clinical, prognostic and predisposing profiles in 119 cases of dissection and/or aneurysm occuring 1 month to 16 years after routine AVR were analyzed comprising 62 cases from our database and 57 reported cases. Results: Dissection after AVR has been observed in 0.6 % of all routine AVR procedures in the past four decades. With clinical signs, symptoms and anatomical features different from classic aortic dissection post-AVR dissection is a distinct clinical entity with a high intraoperative mortality of 44 % and a 30-day and 5-year survival of 62 % and 43 %, respectively. Aortic regurgitation and a thin and/or fragile aortic wall at AVR, however, predict late dissection. Using a prediction model, the risk of late dissection can be stratified based on information obtained during AVR surgery. Conclusions: Aortic dissection following AVR is likely to represent a distinct clinical entity which can be predicted and possibly prevented at AVR.
Key words:
Aneurysm - Aorta - Risk factors - Surgery - Valves
1 The material of this manuscript was presented at the International Congress on “Risk Stratification in Cardiac and Thoracic Surgery”, October 15/16, 1999, Cologne, Germany.
References
1
von Kodolitsch Y, Simic O, Dresler C, Haverich, Nienaber C A.
Aortic valve replacement: An independent predisposing factor for late aortic dissection?.
Circulation.
1997;
96
I-507 (A)
2
von Kodolitsch Y, Simic O, Bregenzer T, Dresler C, Haverich, Nienaber C A.
Der Aortenklappenersatz als unabhängiger prädiktiver Faktor für die Entstehung einer späten Aortendissektion.
Z Kardiol.
1998;
87
604-612
3
von Kodolitsch Y, Simic O, Schwartz A G, Dresler C, Loose R, Staudt M, Ostermeyer J, Haverich A, Nienaber C A.
Predictors of proximal aortic dissection at the time of aortic valve replacement.
Circulation.
1999;
100
II-287-II-294
4
Muna W F, Spray T L, Morrow A G, Roberts W C.
Aortic dissection after aortic valve replacement in patients with valvular aortic stenosis.
J Thorac Cardiovasc Surg.
1977;
74
65-69
7
Cohn L H, Allred E N, DiSesa V J, Sawtelle K, Shemin R J, Collins J J.
Early and late risk of aortic valve replacement. A 12 year concomitant comparison of the porcine bioprosthetic and tilting disc prosthelic aortic valves.
J Thorac Cardiovasc Surg.
1984;
88
695-705
8
Douglas P S, Hirshfeld J W, Edie R N, Harken A H, Stephenson L W, Edmunds L H.
Clinical comparison of St. Jude and porcine aortic valve prostheses.
Circulation.
1985;
72
II-135-II-139
9
Lytle B W, Cosgrove D M, Taylor P C, Goormastic M, Stewart R W, Golding L A R, Gill C C, Loop F D.
Primary isolated aortic valve replacement. Early and late results.
J Thorac Cardiovasc Surg.
1989;
97
675-694
12
Presbitero P, Aruta E, Rabajoli F, Agaccio G, Donegani E, Orzan F, Malara D, Di Summa M, Morea M.
Aortic dissection after aortic valve replacement: clinical and anatomic features.
G Ital Cardiol.
1993;
22
941-947
13
Aris A, Padró J M, Cámara M L, Lapiedra O, Caralps J M, Borrás Y, Carreras F, Pons-Lladó G.
The monostrut Bjork-Shiley valve. Seven years' experience.
J Thorac Cardiovasc Surg.
1992;
103
1074-1082
16
Miller D C, Mitchell R S, Oyer P E, Stinson E B, Jamieson S W, Shumway N E.
Independent determinations of operative mortality for patients with aortic dissectios.
Circulation.
1984;
70
I-153-I-164
18
Epperlein S, Mohr-Kahaly S, Erbel R, Kearney P, Meyer J.
Aorta and aortic valve morphologies predisposing to aortic dissection. An in vivo assessment with transesophageal echocardiography.
Eur J Cardiol.
1994;
15
1520-1527
23
Gooch A S.
Downward displacement of competent aortic valve prosthesis without left ventricular enlargement: A new sign of ascending aortic root dissection in absence of valvular regurgitation.
Am Heart J.
1982;
103
920-922
24
Orszulak T A, Pluth J R, Schaff H V, Piehler J M, Smith H C, McGoon D C.
Results of surgical treatment of ascending aortic dissections occuring late after cardiac operation.
J Thorac Cardiovasc Surg.
1982;
83
538-545
25
Le Heuzey J Y, Guize L, Guerinon J, Forman J, Sellier P, Maurice P.
Dissection de I'aorte ascendante apres replacement valvulaire aortique.
Arch Mal Coeur.
1983;
11
1349-1356
26
Stone D L, Petch M C, Verney G I, Dixon A K.
Superior mediastinal obstruction with aortic dissection after aortic valve replacement. Diagnosis by computed tomography.
Br Heart J.
1984;
51
565-567
30
Hirao D, Ishikura Y, Odagiri S, Shimazu A, Yano K, Shirakusa T.
A case report of type II dissecting aneurysm after aortic valve replacement, successful repair by the modified Cabrol's method.
J Jpn Assoc Thorac Surg.
1991;
39
1940-1944
32
Osada T, Nagae T, Hirayama T, Ishimura S, Furukawa K.
A case of ascending aortic dissection after aortic valve replacement in congenital bicuspide aortic valve.
J Jpn Assoc Thorac Surg.
1992;
40
1928-1932
33
Tayama K, Aoyagi S, Akashi H, Oryoji A, Higa Y, Hiromatsu S, Yamana K, Kosuga K, Ohishi K.
Aortic dissection after aortic valve replacement. Report of a case with an aortocameral fistula.
Thorac Cardiovasc Surgeon.
1995;
43
299-301
36
Stone P H, Clark R D, Goldschlager N, Selzer A, Cohn K.
Determinants of prognosis of patients with aortic regurgitation who undergo aortic valve replacement.
JACC.
1984;
3
1118-1126
37
Czer L S C, Gray R J, Stewart M E, De Robertis M, Chaux A, Matloff J M.
Reduction in sudden late death by concomitant revascularization with aortic valve replacement.
J Thorac Cardiovasc Surg.
1988;
95
390-401
38
von Kodolitsch Y, Nienaber C A.
Die intramurale Hamorrhagie der thorakalen Aorta: Diagnostik, Therapie und Prognose bei 209 in vivo diagnostizierten Fallen.
Z Kardiol.
1998;
87
797-807
40
Pieters F A A, Widdershoven J W, Gerardy A-C, Geskes G, Cheriex E C, Wellens H J.
Risk of aortic dissection after aortic valve replacement.
Am JCardiol.
1993;
72
1043-1047
2 Y. von Kodalitsch is supported by grants of the Deutsche Forschungsgemeinschaft (KO 1828/1 and KO 1828/ 1-2)
1 The material of this manuscript was presented at the International Congress on “Risk Stratification in Cardiac and Thoracic Surgery”, October 15/16, 1999, Cologne, Germany.
Dr. Y. von Kodolitsch
Department of Internal Medicine Division of Cardiology University Hospital Eppendorf