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Am J Perinatol 2001; 18(1): 011-014
DOI: 10.1055/s-2001-12936
Original Articles
Copyright © 2001 by Thieme Medical Publishers, Inc., 333 Seventh Avenue, New York, NY 10001, USA. Tel.: +1(212) 584-4662

Aneurysm of the Ductus Arteriosus in a Neonate with 13q-Deletion

G. Naulaers1 , K. Devriendt2 , Ph. Moerman3 , P. Gillis4 , C. Vanhole1 , H. Devlieger1
  • 1Neonatal Intensive Care Unit, Department of Paediatrics, UZ Gasthuisberg, Leuven, Belgium
  • 2Centre for Human Genetics, UZ Gasthuisberg, Leuven, Belgium
  • 3Department of Pathology, UZ Gasthuisberg, Leuven, Belgium
  • 4Department of Paediatrics, Virga Jesse Ziekenhuis, Hasselt, Belgium
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Publication History

Publication Date:
31 December 2001 (online)

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ABSTRACT

Aneurysm of the ductus arteriosus is a rare abnormality for which different ways of pathogenesis are described. We report the case of a fatal thrombosis of an aneurysm of the ductus arteriosus in an infant presenting feeding difficulties and a mild dysmorphic facies. Karyotype analysis revealed a de novo chromosomal deletion 46,XY, del (13)(q12.3,q22.3). To the best of our knowledge, this is the first case of an aneurysm of the ductus arteriosus associated with a chromosomal aberration.

KEYWORD

Chromosome 13 - deletion - aneurysm - ductus arteriosus - congenital heart disease

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