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Semin Respir Crit Care Med 2001; 22(1): 013-022
DOI: 10.1055/s-2001-13836
Copyright © 2001 by Thieme Medical Publishers, Inc., 333 Seventh Avenue, New York, NY 10001, USA. Tel.: +1(212) 584-4662

Smoke Inhalation Injury

Barbara A. Latenser1 , Lawrence Iteld2
  • 1Department of Trauma, Cook County Hospital, Chicago, Illinois
  • 2University of Chicago
Further Information

Publication History

Publication Date:
31 December 2001 (online)

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ABSTRACT

Smoke inhalation injuries are the leading cause of fatalities from burn injury. The major forms of inhalation injuries are carbon monoxide toxicity, injury to the upper airway, and pulmonary parenchymal damage. The compromised airway is protected by tracheal intubation, and respiratory failure is treated with assisted ventilation. Maintenance of good pulmonary hygiene, optomized fluid resuscitation, and routine invasive hemodynamic monitoring are the mainstays of therapy. The development of acute pulmonary insufficiency, pulmonary edema, or bronchopneumonia requires a comprehensive approach to all aspects of the illness. Acute pathophysiologic responses to inhalation injury are complex. Future therapies will target improved ventilatory strategies and the redundant host inflammatory response.

KEYWORD

Smoke inhalation injury - burns - ventilation

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