Antioxidant Activity of Leaves of Salvia Species in Enzyme-Dependent and Enzyme-Independent Systems of Lipid Peroxidation and their Phenolic Constituents

István Zupkó; Judit Hohmann; Dóra Rédei; György Falkay; Gábor Janicsák; Imre Máthé

doi:10.1055/s-2001-14327

Planta Medica, Table of Contents

Planta Med 2001; 67(4): 366-368
DOI: 10.1055/s-2001-14327

Letter

Antioxidant Activity of Leaves of Salvia Species in Enzyme-Dependent and Enzyme-Independent Systems of Lipid Peroxidation and their Phenolic Constituents

István Zupkó¹ , Judit Hohmann^2,*, Dóra Rédei² , György Falkay¹ , Gábor Janicsák³ , Imre Máthé^{1, 3}

¹ Department of Pharmacodynamics and Biopharmacy, University of Szeged, Szeged, Hungary
² Department of Pharmacognosy, University of Szeged, Szeged, Hungary
³ Institute of Ecology and Botany of the Hungarian Academy of Sciences, Vácrátót, Hungary

Abstract

The protective effects of eleven Salvia species native to Europe against enzyme-dependent and enzyme-independent lipid peroxidation were evaluated. The 50 % aqueous methanolic extracts of the leaves of all tested plants were found to be more effective than the positive control α-tocopherol acid succinate. The extracts of S. candelabrum, S. ringens, S. tomentosa, S. nemorosa, and S. glutinosa displayed considerable concentration-dependent antioxidative effects that were comparable to those of the medicinal and aromatic plant S. officinalis. The concentrations of flavonoids, hydroxycinnamic acids and total phenolic compounds in each extract were quantified with the aim of clarifying the connection between activity and chemical composition.

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Dr. Judit Hohmann

Department of Pharmacognosy

University of Szeged

P.O. Box 121

6701 Szeged

Hungary

Email: hohmann@pharma.szote.u-szeged.hu

Fax: +(36)62 545 704