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Semin Respir Crit Care Med 2001; 22(3): 281-292
DOI: 10.1055/s-2001-15785
Copyright © 2001 by Thieme Medical Publishers, Inc., 333 Seventh Avenue, New York, NY 10001, USA. Tel.: +1(212) 584-4662

Acute Respiratory Distress Syndrome: Adjuncts to Lung-Protective Ventilation

John P. Kress1 , John J. Marini2
  • 1Department of Medicine, Section of Pulmonary and Critical Care, University of Chicago, Chicago, Illinois
  • 2Department of Pulmonary and Critical Care Medicine, University of Minnesota, St. Paul, Minnesota
Further Information

Publication History

Publication Date:
31 December 2001 (online)

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ABSTRACT

Despite recent advances in understanding, the management of acute respiratory distress syndrome (ARDS) remains a challenging clinical problem. Optimization of gas exchange and preventing the iatrogenic propagation of lung injury are cornerstones of its clinical management. A number of novel approaches and adjuncts to mechanical ventilation have been described over the past decade to help achieve these goals, and some have been widely implemented with varying degrees of success. This chapter will review the rationale and evidence supporting the use of such adjunctive strategies.

KEYWORD

ARDS - permissive hypercapnia - barotrauma - perflubron - prone position - nitric oxide - extracorporeal circulation - surfactant

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