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Endoscopy 2001; 33(11): 909-916
DOI: 10.1055/s-2001-17926
DDW Reports 2001
© Georg Thieme Verlag Stuttgart · New York

Gastroesophageal Reflux Disease and Barrett’s Esophagus

T. Rösch
  • Dept. of Internal Medicine II, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany
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Publication History

Publication Date:
18 October 2001 (online)

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This year’s Digestive Disease Week (DDW) once again saw a large number of abstracts on gastroesophageal reflux disease (GERD) and Barrett’s esophagus (BE), with a special emphasis on diagnostic aspects using magnification endoscopy and on the new antireflux therapies. This review focuses on highlights from these abstracts.

References

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  • 2 Johanson J, Hwang C, Roach A. Prevalence of erosive esophagitis (EE) in patients with gastroesophageal reflux disease (GERD) [abstract].  Gastroenterology. 2001;  120 A 233
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  • 3 Fujiwara Y, Higuchi K, Tominaga K, et al. Association between gastroesophageal flap valve, reflux esophagitis, Barrett’s epithelium, and atrophic gastritis assessed by endoscopy in Japanese patients [abstract].  Gastrointest Endosc. 2001;  53 AB 142
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  • 21 Kearney D J, Crump C, Maynard C, et al. A case-control study of endoscopy and mortality from adenocarcinoma of the esophagus of gastric cardia (AEGC) for persons with gastroesophageal reflux disease (GERD) [abstract].  Gastroenterology. 2001;  120 A 414
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  • 24 Sampliner R E, Eisen G M, DeGarmo P. Ethnicity and gender of patients with suspected Barrett’s esophagus in a large endoscopy cohort (CORI) [abstract].  Gastrointest Endosc. 2001;  53 AB 151
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  • 25 Sampliner R E, Eisen G M, DeGarmo P. Demographic and clinical risk factors differ between long- and short-segment suspected Barrett’s esophagus [abstract].  Gastrointest Endosc. 2001;  53 AB 155
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  • 26 Goldblum J R, Richter J E, Vaezi M F, et al. H. pylori (HP), not GERD, is the major cause of inflammation and intestinal metaplasia (IM) of the native gastric cardia [abstract].  Gastroenterology. 2001;  120 A 412
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  • 27 Lung E, Levin T R, Habel L, et al. Prevalence of gastric metaplasia without intestinal metaplasia among patients with adenocarcinoma of the esophagus [abstract].  Gastrointest Endosc. 2001;  53 AB 146
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  • 28 Souto E O, Cameron A J, Smyrk T C. Small adenocarcinomas of the cardia: association with intestinal metaplasia and dysplasia [abstract].  Gastroenterology. 2001;  120 A 442-A 443
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  • 30 Gerson L B, Shetler K, Triadafilopoulos G. Screening for Barrett’s esophagus in asymptomatic adults undergoing routine flexible sigmoidoscopy for colorectal cancer screening [abstract].  Gastrointest Endosc. 2001;  53 AB 61
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  • 33 Saeian K, Vasipoulos S, Staff D, et al. Does biopsy size of unsedated transnasal endoscopy (T-EGD) impact histologic interpretation of Barrett’s dysplasia? [abstract].  Gastrointest Endosc. 2001;  53 AB 157
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  • 34 Weinstein W M, Leh W W, Wiggett S D. False-positive diagnoses of Barrett’s esophagus are common. Why do they occur? [abstract].  Gastroenterology. 2001;  120 A 442
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  • 35 Dave U, Mahadeva U, Loh V, et al. Peri-Z-line biopsy routine upper GI endoscopy: from where and how many? [abstract].  Gastroenterology. 2001;  120 A 428
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  • 36 Chauhan T C, Waxman M, Ho I K. Nonulcer dyspepsia and intestinal metaplasia (IM) of the gastric cardia [abstract].  Gastrointest Endosc. 2001;  53 AB 219
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  • 37 Huh C, Henry M, Darwin P E. Brush cytology via unsedated esophagoscopy for the diagnosis of Barrett’s esophagus [abstract].  Gastrointest Endosc. 2001;  53 AB 158
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  • 38 Falk G W, Provencher K A, Gramlich T L, et al. Surveillance of Barrett’s esophagus with a modified nonendoscopic cytology device: a pilot study [abstract].  Gastrointest Endosc. 2001;  53 AB 157
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  • 39 Glickman J N, Ormsby A H, Gramlich T H, et al. Interinstitutional variability in the interpretation of cytokeratin 7/20 (CK 7/20) staining patterns in Barrett’s esophagus (BE) [abstract].  Gastroenterology. 2001;  120 A 415
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  • 40 Mullic T, Tasch J E, Ormsby A H, et al. Telomerase: a potential biomarker of adenocarcinoma in Barrett’s esophagus [abstract].  Gastroenterology. 2001;  120 A 413
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  • 41 Dulai G S, Ganz P, Kahn K, et al. Barrett’s screening practices of primary care providers in California [abstract].  Gastrointest Endosc. 2001;  53 AB 192
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  • 42 Pruthi J S, Dulai G S, Elguindy A, et al. Barrett’s esophagus: surveillance in an HMO setting [abstract].  Gastrointest Endosc. 2001;  53 AB 160
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  • 43 Dulai G S, Chen J, Oh D, et al. Cancer risk, EGD biopsy workload and reporting in a VA Barrett’s cohort [abstract].  Gastroenterology. 2001;  120 A 416-A 417
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  • 44 Quinonez N F, Rodriguez E D. Length of Barrett’s esophagus and risk of dysplasia in Hispanics [abstract].  Gastroenterology. 2001;  120 A 418
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  • 45 Ronkrainen J, Aro P, Storskrubb T, et al. How persistent is short-segment Barrett’s esophagus in the general population? A report from the Kalixanda study [abstract].  Gastroenterology. 2001;  120 A 232-A 233
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  • 46 Sharma P, Reker D, Falk G W, et al. Progression of Barrett’s esophagus to high-grade dysplasia and cancer: preliminary results of the BEST (Barrett’s Esophagus Study Trial) [abstract].  Gastroenterology. 2001;  120 A 16-A 17
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  • 47 Corley D A, Levin T R, Habel L, et al. Association between surveillance and survival in Barrett’s adenocarcinoma: a population-based study [abstract].  Gastroenterology. 2001;  120 A 17
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  • 48 Dar M, Goldblum J R, Rice T W, et al. Unifocal versus multifocal high-grade dysplasia in Barrett’s esophagus does not predict adenocarcinoma at esophagectomy [abstract].  Gastroenterology. 2001;  120 A 416
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  • 49 Sontag S J, Schnell T G, Chejfec G, et al. Dysplasia: negative for, indefinite for, and low grade have no prognosis value for Barrett’s cancer [abstract].  Gastroenterology. 2001;  120 A 403
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  • 50 Murray L M, Watson R GP, Johnston B T, et al. Low risk of adenocarcinoma in Barrett’s oesophagus: results of a population-based study [abstract].  Gastroenterology. 2001;  120 A 414
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  • 51 Provenzale D. Immediate esophagectomy or continued surveillance for Barrett’s patients with high-grade dysplasia? A decision analysis [abstract].  Gastroenterology. 2001;  120 A 414
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  • 52 Vazquez-Iglesias J L, Canalejo J, Gonzalez-Conde J, et al. The usefulness of methylene blue staining for the detection of intestinal metaplasia of the gastric cardia [abstract].  Gastrointest Endosc. 2001;  53 AB 120
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  • 53 Sharma P, Weston A P, Sampliner R E. Magnification chromoendoscopy for the detection of intestinal metaplasia and dysplasia in Barrett’s esophagus [abstract].  Gastrointest Endosc. 2001;  53 AB 62
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  • 54 Shrestha S, Xiao S Y, Reeves A L, et al. Can high resolution and high-magnification endoscopy (HRHME) accurately predict the presence of specialized intestinal metaplasia in patients with Barrett’s esophagus and serve as a surrogate optical biopsy? [abstract].  Gastrointest Endosc. 2001;  53 AB 121
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  • 55 DeWeerth A, Brand B, Fritscher-Ravens A, et al. High-resolution zoom endoscopy combined with vital staining for improved accurate detection of dysplasia in Barrett’s mucosa: preliminary results from an ongoing study [abstract].  Gastrointest Endosc. 2001;  53 AB 160
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  • 56 Canto M IF, Wu T T, Kalloo A N. High-magnification endoscopy with methylene blue chromoendoscopy for improved diagnosis of Barrett’s esophagus and dysplasia [abstract].  Gastrointest Endosc. 2001;  53 AB 159
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  • 57 Sueoka N, Tabuchi M, Nishigaki H, et al. Magnification endoscopy with vital dye staining for detection of a minute focus of early adenocarcinoma in Barrett’s esophagus [abstract].  Gastrointest Endosc. 2001;  53 AB 150
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  • 58 Ponchon T, Chavaillon A, Saurin J C, et al. Detection of high-grade dysplasia and superficial carcinoma on Barrett’s esophagus by chromoscopy and magnification [abstract].  Gastrointest Endosc. 2001;  53 AB 151
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  • 59 Banerjee B, Agarwal S, Chandrasekhar H R. Autofluorescence spectroscopy to differentiate high-grade dysplasia and cancer from low-grade dysplasia in Barrett’s esophagus [abstract].  Gastrointest Endosc. 2001;  53 AB 153
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  • 60 Haringsma J, Tytgat N J. Fluorescence imaging of high-grade dysplasia in Barrett’s esophagus [abstract].  Gastrointest Endosc. 2001;  53 AB 148
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  • 61 Wang K K, Buttar N S, Wong Kee Song L M, et al. The use of an optical biopsy system in Barrett’s esophagus [abstract].  Gastroenterology. 2001;  120 A 413
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  • 62 Zuccaro G, Gladkova N, Vargo J J, et al. Optical coherence tomography (OCT) in the diagnosis of Barrett’s esophagus (BE), high-grade dysplasia (HGD), intramucosal adenocarcinoma (IMAC) and invasive adenocarcinoma (INVAC) [abstract].  Gastrointest Endosc. 2001;  53 AB 62
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  • 63 Poneros J M, Tearney G J, Bouma B E, et al. Diagnosis of dysplasia in Barrett’s esophagus using optical coherence tomography [abstract].  Gastrointest Endosc. 2001;  53 AB 113
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  • 64 Wong K ee, Shim M G, Wilson B C, et al. In vivo endoscopic Raman spectroscopy for the differentiation of dysplasia (low-grade versus high-grade) within Barrett’s esophagus [abstract].  Gastrointest Endosc. 2001;  53 AB 109
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  • 65 Dulai G S, Jensen D M, Weinstein W M, et al. Screening of patients referred for a Barrett’s ablation protocol: findings and implications for patients and providers [abstract].  Gastrointest Endosc. 2001;  53 AB 158
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  • 66 Tsai P I, Wickramsinghe K, Bremner C G, et al. Barrett’s mucosal thickness: a consideration during ablation [abstract].  Gastroenterology. 2001;  120 A 410
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  • 67 Overholt B F, Panjehpour M, Haydek J M, et al. Photodynamic therapy (PDT) for Barrett’s esophagus with dysplasia: long-term results [abstract].  Gastrointest Endosc. 2001;  53 AB 73
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  • 68 Beejay U, Ribeiro A, Hourigan L, et al. Photodynamic therapy of high-grade dysplasia/intramucosal carcinoma in Barrett’s esophagus: 30 months’ follow-up [abstract].  Gastrointest Endosc. 2001;  53 AB 144
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  • 69 Kahaleh M, van Laethem J L, Nagy N, et al. Long-term follow-up and predictive factors of recurrence in Barrett’s esophagus treated by argon plasma coagulation and omeprazole [abstract].  Gastroenterology. 2001;  120 A 411-A 412
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  • 70 Morris C D, Byrne J P, Attwood S E. Endoscopic ablation of Barrett’s esophagus by argon beam plasma coagulation: long-term follow-up [abstract].  Gastrointest Endosc. 2001;  53 AB 145
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  • 71 Familiari L, Bonica M, Consolo P, et al. Endoscopic argon-plasma coagulation (APC) of Barrett’s esophagus: long-term follow-up [abstract].  Gastrointest Endosc. 2001;  53 AB 158
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  • 72 Fusaroli P, Togliani T, Eleonori S, et al. Endoscopic argon plasma coagulation for reversal of Barrett’s metaplasia: the shorter the better? [abstract].  Gastrointest Endosc. 2001;  53 AB 148
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  • 73 Pereira-Lima J C, Toneloto E B, Lopes C V, et al. High power-setting argon plasma coagulation ablates Barrett’s esophagus without leaving intestinal metaplasia underneath the new squamous epithelium [abstract].  Gastrointest Endosc. 2001;  53 AB 37
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  • 74 Burdick J S, Dykes C M, Lindberg G M, et al. Factors which influence the efficacy of PDT in HGD and adenocarcinoma of the esophagus [abstract].  Gastrointest Endosc. 2001;  53 AB 141
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  • 75 Schattner M A, da Carlsson M, Ahdoot A, et al. Risk factors for photodynamic therapy induced strictures of the esophagus [abstract].  Gastrointest Endosc. 2001;  53 AB 159
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  • 76 Wang K K, Lutzke L S, Buttar N S, et al. Do non-steroidal anti-inflammatory drugs (NSAIDS) influence treatment outcome in photodynamic therapy (PDT) of Barrett’s esophagus? [abstract].  Gastrointest Endosc. 2001;  53 AB 156
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  • 77 Krishnadath K, Wang K K, Taniguchi K, et al. Mutations in Barrett’s esophagus predict poor response to photodynamic therapy [abstract].  Gastroenterology. 2001;  120 A 413
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  • 78 Morris C D, Tselepis C, Harrison R, et al. Characterization of classical and desmosomal cadherins in the neo-squamous epithelium after endoscopic ablation of Barrett’s esophagus [abstract].  Gastroenterology. 2001;  120 A 416
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  • 79 Lenz M, Hoepfner M, Theiss A, et al. Hypericin is an encouraging new photosensitizer for photodynamic therapy of esophageal dysplasia/cancer: antiproliferative and apoptotic effects [abstract].  Gastroenterology. 2001;  120 A 443
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  • 80 Fass R, Garewal H S, Pulliam G, et al. Chemoreceptor sensitivity and esophageal motor function before and after reversal of Barrett’s esophagus (BE) with endoscopic multipolar electrocoagulation (MPEC) [abstract].  Gastroenterology. 2001;  120 A 415
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  • 81 Giovannini M, Bories E, Ries P, et al. Long-term follow-up of patients treated by endoscopic mucosal resection (EMR) guided by high-frequency EUS for superficial esophageal cancer [abstract].  Gastroenterology. 2001;  120 A 442
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  • 82 Ponchon T, Saurin J C. Circumferential endoscopic mucosal resection for Barrett’s esophagus: in vitro studies on pigs [abstract].  Gastrointest Endosc. 2001;  53 AB 159
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  • 83 Rajan E, Burgart L J, Herman L J, et al. Widespread endoscopic mucosal resection (WEMR) of the esophagus with strategies for stricture prevention [abstract].  Gastrointest Endosc. 2001;  53 AB 126
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  • 84 Eastone J A, Horwhat D, Haluska O, et al. Cryoablation of swine esophageal mucosa: a direct comparison to argon plasma coagulation (APC) and multipolar electrocoagulation (MPEC) [abstract].  Gastrointest Endosc. 2001;  53 AB 121
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T.  Rösch, M.D.

Dept. of Internal Medicine II
Klinikum rechts der Isar
Technical University of Munich

Ismaningerstrasse 22
81675 München
Germany


Fax: + 49-89-4140-4872

Email: thomas.roesch@lrz.tum.de