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Planta Med 2001; 67(9): 880-883
DOI: 10.1055/s-2001-18851
Letter

© Georg Thieme Verlag Stuttgart · New York

Composition of the Essential Oil of Two Nepeta Species and in vitro Evaluation of their Activity against Helicobacter pylori

Eleftherios Kalpoutzakis1 , Nektarios Aligiannis1 , Andreas Mentis2 , Sofia Mitaku1 , Catherine Charvala1
  • 1 Division of Pharmacognosy, School of Pharmacy, University of Athens, Panepistimiopolis Zografou, Athens, Greece
  • 2 Laboratory of Bacteriology, Hellenic Pasteur Institute, Athens, Greece
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Publication History

December 8, 2000

March 21, 2001

Publication Date:
06 December 2001 (online)

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Abstract

The chemical composition of the essential oils obtained from the aerial parts of Nepeta camphorata and Nepeta argolica ssp. dirphya were analysed by GC-MS. A total of 52 components were identified and significant differences (qualitative and quantitative) were observed between the two samples. 1,8-Cineol and two nepetalactones were found to be the major components of the oil of N. camphorata and N. argolica ssp. dirphya respectively. The in vitro activity, of the two oils and the three above mentioned isolated compounds, against 25 clinically isolated and commercial strains of Helicobacter pylori was investigated and some activity was found.

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Pr. S. Mitaku

Division of Pharmacognosy

School of Pharmacy

University of Athens

Panepistimiopolis Zografou

Athens 15771

Greece

Email: mitakou@pharm.uoa.gr

Fax: +30-1-7274594