Abstract
This review presents the progress in hydrogenated pyrrolopyridine synthesis and reactivity studies over the last 20 years. The emphasis has been made on the methods of synthesis and reactivity of the tetrahydrogenated derivatives, especially tetrahydropyrrolo[3,2-c ]pyridines.
1 Introduction
2 Synthesis of Hydrogenated Pyrrolopyridines
2.1 Tetrahydropyrrolo[3,2-c ]pyridines
2.2 Tetrahydropyrrolo[2,3-c ]pyridines
2.3 Tetrahydropyrrolo[3,2-b ]pyridines
2.4 Tetrahydropyrrolo[3,4-b ]pyridines
2.5 Dihydro- and Hexahydropyrrolo[2,3-b ]pyridines
2.6 Hexahydropyrrolo[3,2-c ]pyridines
2.7 Hexahydropyrrolo[3,4-c ]pyridines
2.8 Di- and Hexahydropyrrolo[3,4-b ]pyridines
2.9 Perhydropyrrolopyridines (PHPP)
3 Reactivity of Hydrogenated Pyrrolopyridines (PP)
3.1 Reactions at the Pyrrole Ring
3.2 Reactions at the Tetrahydropyridine Ring
4 Conclusions
Key words
pyrrolopyridines - fused heterocyclic systems - pyrrole - heterocylization
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