Coexistence of Non-Hodgkin’s Lymphoma and Non-Small-Cell Lung Carcinoma: Diagnosis and Treatment

M. Rothenburger; M. Semik; A. Hoffmeier; H. Baba; D. Kamanabrou; N. Roos; C. Schmidt; H. H. Scheld

doi:10.1055/s-2002-20154

The Thoracic and Cardiovascular Surgeon, Table of Contents

Thorac Cardiovasc Surg 2002; 50(1): 59-61
DOI: 10.1055/s-2002-20154

Case Report

Coexistence of Non-Hodgkin’s Lymphoma and Non-Small-Cell Lung Carcinoma: Diagnosis and Treatment

M. Rothenburger¹ , M. Semik¹ , A. Hoffmeier¹ , H. Baba² , D. Kamanabrou³ , N. Roos⁴ , C. Schmidt⁵ , H. H. Scheld¹

¹Department of Cardiothoracic Surgery, University of Muenster, Germany,
²Gerhard Domagk Institute for Pathology, University of Muenster, Germany,
³Department of Dermatology and Reconstructive Surgery, Fachklinik Hornheide, Muenster, Germany,
⁴Institute of Clinical Radiology, University of Muenster, Germany,
⁵Department of Anesthesiology and Operative Intensive Care Medicine, University of Muenster, Germany,

Abstract

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Abstract

In this communication, we will present a very rare case of the coexistence of non-Hodgkin’s lymphoma (NHL; low malignant lymphocytic lymphoma of the B-cell type) and a non-small-cell lung carcinoma (NSCLC). A patient with a 15-year history of NHL developed a generalized relapse of the lymphoma with an additional tumor mass in the left lower lobe of the lung. Bronchoscopy showed the evidence of the NHL. Due to non-responding chemotherapy on the lung tumor, the coexistence of a second malignancy was histologically proved in a second bronchoscopy. Resection of the lung tumor with complex lobectomy and lymphadenectomy was performed. After that, chemotherapy with four cycles of carboplatin supplemented with taxol was induced. The patient was discharged from the hospital with a stable remission of both tumor diseases. Restaging after six months showed no evidence of a tumor relapse. This is a very rare case of the coexistence of NHL and NSCLC; we will discuss the difficulty of diagnostic and treatment of both tumor diseases.

Key words

NHL - NSCLC - Chemotherapy

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References

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Dr. Markus Rothenburger

Department of Cardiothoracic Surgery
University of Muenster

Albert-Schweitzer-Straße 33

48129 Muenster

Germany

Phone: +49 (251) 83-47401

Fax: +49 (251) 83-48316

Email: markus.rothenburger@thgms.uni-muenster.de