Planta Med 2002; 68(2): 146-151
DOI: 10.1055/s-2002-20248
Original Paper
Natural Product Chemistry
© Georg Thieme Verlag Stuttgart · New York

Cytotoxic Coumaronochromones from the Roots of Euchresta formosana

Wen-Li Lo1 , Fang-Rong Chang1 , Chih-Chuang Liaw1 , Yang-Chang Wu1
  • 1Graduate Institute of Natural Products, Kaohsiung Medical University, Kaohsiung, Taiwan
Further Information

Publication History

March 16, 2001

June 3, 2001

Publication Date:
22 February 2002 (online)

Abstract

Five new coumaronochromones, euchretins J-N (1 - 5), along with twelve known compounds, euchretins A (6), C, D, F, H, I, (+)-matrine, (-)-cytisine, quercetin, trifolirhizin, retusin 8-methyl ether, and genistein, were isolated from the methanolic extracts of Euchresta formosana. The structures of compounds 1 - 5 were established by spectroscopic analyses. Among them, compounds 1, 4 and 6 were demonstrated to have cytotoxicity against 59T cell line, and compound 1 was also found to be active against SCM-1 cell line.

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Dr. Yang-Chang Wu

Graduate Institute of natural Products

Kaohsiung Medical University

Kaohsiung 807

Taiwan

Phone: +886-7-312-1101 ext. 2197

Fax: +886-7-3114773

Email: yachwu@cc.kmu.edu.tw.