10 Literatur
- 1
Potten C S, Loeffler M.
Stem cells: attributes, cycles, spirals, pitfalls and uncertainties. Lessons for and
from the crypt.
Development.
1990;
110
1001-1020
- 2
Dym M.
Spermatogonial stem cells of the testis.
Proc Natl Acad Sci USA.
1994;
91
11 287-11 289
- 3
Lavker R M, Miller S, Wilson C, Cotsarelis G, Wei Z G, Yang J S, Sun T T.
Hair follicle stem cells: their location, role in hair cycle, and involvement in skin
tumor formation.
Journal of Investigative Dermatology.
1993;
101
16S-26S
- 4
Graziadei P P, Monti Graziadei G A.
Neurogenesis and neuron regeneration in the olfactory system of mammals. III. Deafferentation
and reinnervation of the olfactory bulb following section of the fila olfactoria in
rat.
Journal of Neurocytology.
1980;
9
145-162
- 5
Gage F H.
Mammalian neural stem cells.
Science.
2000;
287
1433-1438
- 6
Weissman I.
Stem cells: units of development, units of regeneration, and units in evolution.
Cell.
2000;
100
157-168
- 7
Sigal S H, Brill S, Fiorino A S, Reid L M.
The liver as a stem cell and lineage system.
American Journal of Physiology.
1992;
263
G139-148
- 8 Loeffler M, Potten C S.
Stem cells and cellular pedigrees - a conceptual introduction. In: Potten CS, ed Stem cells. London; Academic Press 1997: 1-27
- 9
Whetton A D, Graham G J.
Homing and mobilization in the stem cell niche.
Trends Cell Biol.
1999;
9
233-238
- 10
Huang S, Law P, Francis K, Palsson B O, Ho A D.
Symmetry of Initial Cell Divisions Among Primitive Hematopoietic Progenitors Is Independent
of Ontogenic Age and Regulatory Molecules.
Blood.
1999;
94
2595-2604
- 11
Ema H, Nakauchi H.
Expansion of hematopoietic stem cells in the developing liver of a mouse embryo.
Blood.
2000;
95
2284-2288
- 12
Qian X, Goderie S K, Shen Q, Stern J H, Temple S.
Intrinsic programs of patterned cell lineages in isolated vertebrate CNS ventricular
zone cells.
Development.
1998;
125
3143-3152
- 13
Bonifer C, Faust N, Geiger H, Müller A M.
Developmental changes in the differentiation capacity of haematopoietic stem cells.
Immunology Today.
1998;
19
236-241
- 14
Qian X, Shen Q, Goderie S K, He W, Capela A, Davis A A, Temple S.
Timing of CNS cell generation: a programmed sequence of neuron and glial cell production
from isolated murine cortical stem cells.
Neuron.
2000;
28
69-80
- 15
Kirchhof N, Harder F, Petrovic S, Kreutzfeldt S, Schmittwolf C, Dürr M, Mühl B, Merkel A,
Müller A M.
Developmental potential of hematopoietic and neural stem cells: unique or all the
same?.
Cells Tissues Organs (in press).
2002;
- 16
Phillips R L, Ernst R E, Brunk B, Ivanova N, Mahan M A, Deanehan J K, Moore K A, Overton G C,
Lemischka I R.
The genetic program of hematopoietic stem cells.
Science.
2000;
288
1635-1640
- 17
Geschwind D H, Ou J, Easterday M C, Dougherty J D, Jackson R L, Chen Z, Antoine H,
Terskikh A, Weissman I L, Nelson S F, Kornblum H I.
A genetic analysis of neural progenitor differentiation.
Neuron.
2001;
29
325-339
- 18
Evans M J, Kaufman M H.
Establishment in culture of pluripotential cells from mouse embryos.
Nature.
1981;
292
154-156
- 19
Martin G R.
Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned
by teratocarcinoma stem cells.
Proc Natl Acad Sci USA.
1981;
78
7634-7638
- 20
Dani C, Smith A G, Dessolin S, Leroy P, Staccini L, Villageois P, Darimont C, Ailhaud G.
Differentiation of embryonic stem cells into adipocytes in vitro.
J Cell Sci.
1997;
110
1279-1285
- 21
Müller A M, Dzierzak E A.
ES cells have only a limited lymphopoietic potential after adoptive transfer into
mouse recipients.
Development.
1993;
118
1343-1351
- 22
Kramer J, Hegert C, Guan K, Wobus A M, Müller P K, Rohwedel J.
Embryonic stem cell-derived chondrogenic differentiation in vitro: activation by BMP-2
and BMP-4.
Mech Dev.
2000;
92
193-205
- 23
Brustle O, Spiro A C, Karram K, Choudhary K, Okabe S, McKay R D.
In vitro-generated neural precursors participate in mammalian brain development.
Proc Natl Acad Sci USA.
1997;
94
14 809-14 814
- 24
Lumelsky N, Blondel O, Laeng P, Velasco I, Ravin R, McKay R.
Differentiation of embryonic stem cells to insulin-secreting structures similar to
pancreatic islets.
Science.
2001;
292
1389-1394
- 25
Capecchi M R.
Altering the genome by homologous recombination.
Science.
1988;
244
1288-1292
- 26
Thomson J A, Itskovitz-Eldor J, Shapiro S S, Waknitz M A, Swiergiel J J, Marshall V S,
Jones J M.
Embryonic stem cell lines derived from human blastocysts.
Science.
1998;
282
1145-1147
- 27
Schuldiner M, Yanuka O, Itskovitz-Eldor J, Melton D A, Benvenisty N.
From the cover: effects of eight growth factors on the differentiation of cells derived
from human embryonic stem cells.
Proc Natl Acad Sci USA.
2000;
97
11 307-11 312
- 28
Müller A M, Medvinsky A, Strouboulis J, Grosveld F, Dzierzak E.
Development of hematopoietic stem cell activity in the mouse embryo.
Immunity.
1994;
1
291-301
- 29
Okada S, Nakauchi H, Nagayoshi K, Nishikawa S-I, Miura Y, Suda T.
In vivo and in vitro stem cell function of c-kit- and Sca-1-positive murine hematopoietic cells.
Blood.
1992;
80
3044-3050
- 30
Fong G-H, Rossant J, Gertsenstein M, Breitman M L.
Role of Flt-1 receptor tyrosine kinase in regulating the assembly of vascular endothelium.
Nature.
1995;
376
66-71
- 31
Porcher C, Swat W, Rockwell K, Fujiwara Y, Alt F W, Orkin S H.
The T cell leukemia oncoprotein SCL/tal-1 is essential for the development of all
hematopoietic lineages.
Cell.
1996;
86
47-57
- 32
Hirsch E, Iglesias A, Potocnik A J, Hartmann U, Fässler R.
Impaired migration but not differentiation of haematopoietic stem cells in the absence
of β1 integrins.
Nature.
1996;
380
171-175
- 33
Arroyo A G, Yang J T, Rayburn H, Hynes R O.
Differential requirements for α4 Integrins during Fetal and Adult Hematopoieis.
Cell.
1996;
85
997-1008
- 34
Escary J L, Perreau J, Dumenil D, Ezine S, Brulet P.
Leukemia inhibitory factor is necessary for maintenance of haematopoietic stem cells
and thymocyte stimulation.
Nature.
1993;
363
361-364
- 35
Bernad A, Kopf M, Kulbacki R, Weich N, Koehler G, Gutierrez-Ramos J C.
Interleukin-6 is required in vivo for the regulation of stem cells and committed progenitors
of the hematopoietic system.
Immunity.
1994;
1
725-731
- 36
Bhatia M, Wang J CY, Kapp U, Bonnet D, Dick J E.
Purification of primitive human hematopoietic cells capable of repopulating immune-deficient
mice.
Proc Natl Acad Sci USA.
1997;
94
5320-5325
- 37
Ziegler B L, Valtieri M, Porada G A, de Maria R, Müller R, Masella B, Gabbianelli M,
Casella I, Pelosi E, Bock T, Zanjani E D, Peschle C.
KDR receptor: a key marker defining hematopoietic stem cells.
Science.
1999;
285
1553-1558
- 38
Weissman I L.
Translating stem and progenitor cell biology to the clinic: barriers and opportunities.
Science.
2000;
287
1442-1446
- 39
McKay R.
Stem cells in the central nervous system.
Science.
1997;
276
66-71
- 40
Reynolds B A, Weiss S.
Generation of neurons and astrocytes from isolated cells of the adult mammalian central
nervous system.
Science.
1992;
255
1707-1710
- 41
Morshead C M, Reynolds B A, Craig C G, McBurney M W, Staines W A, Morassutti D, Weiss S,
van der Kooy D.
Neural stem cells in the adult mammalian forebrain: a relatively quiescent subpopulation
of subependymal cells.
Neuron.
1994;
13
1071-1082
- 42
Davis A A, Temple S.
A self-renewing multipotential stem cell in embryonic rat cerebral cortex.
Nature.
1994;
372
263-266
- 43
Dorrell C, Gan O I, Pereira D S, Hawley R G, Dick J E.
Expansion of human cord blood CD34(+)CD38(-) cells in ex vivo culture during retroviral
transduction without a corresponding increase in SCID repopulating cell (SRC) frequency:
dissociation of SRC phenotype and function.
Blood.
2000;
95
102-110
- 44
Gritti A, Parati E A, Cova L, Frohlichsthal P, Galli R, Wanke E, Faravelli L, Morassutti D J,
Roisen F, Nickel D D, Vescovi A L.
Multipotential stem cells from the adult mouse brain proliferate and self-renew in
response to basic fibroblast growth factor.
Journal of Neurosciences.
1996;
16
1091-1100
- 45
Kempermann G, Kuhn H G, Gage F H.
More hippocampal neurons in adult mice living in an enriched environment.
Nature.
1997;
386
493-495
- 46
Friedenstein A J, Gorskaja J F, Kulagina N N.
Fibroblast precursors in normal and irradiated mouse hematopoietic organs.
Exp Hematol.
1976;
4
267-274
- 47
Fuchs E, Segre J A.
Stem cells: a new lease on life.
Cell.
2000;
100
143-155
- 48
Pittenger M F, Mackay A M, Beck S C, Jaiswal R K, Douglas R, Mosca J D, Moorman M A,
Simonetti D W, Craig S, Marshak D.
Multilineage potential of adult human mesenchymal stem cells.
Science.
1999;
284
143-147
- 49
Geiger H, Sick S, Bonifer C, Müller A M.
Globin gene expression is reprogrammed in chimeras generated by injecting adult hematopoietic
stem cells into mouse blastocysts.
Cell.
1998;
93
1055-1065
- 50
Bjornson C RR, Rietze R L, Reynolds B A, Magli M C, Vescovi A L.
Turning brain into blood: a hematopoietic fate adopted by adult neural stem cells
in vivo.
Science.
1999;
283
534-537
- 51
Galli R, Borello U, Gritti A, Minasi M G, Bjornson C, Coletta M, Mora M, de Angelis M G,
Fiocco R, Cossu G, Vescovi A L.
Skeletal myogenic potential of human and mouse neural stem cells.
Nat Neurosci.
2000;
3
986-991
- 52
Gussoni E, Soneoka Y, Strickland C D, Buzney E A, Khan M K, Flint A F, Kunkel L M,
Mulligan R C.
Dystrophin expression in the mdx mouse restored by stem cell transplantation.
Nature.
1999;
401
390-394
- 53
Jackson K A, Mi T, Goodell M A.
Hematopoietic potential of stem cells isolated from murine skeletal muscle.
Proc Natl Acad Sci USA.
1999;
96
14 482-14 486
- 54
Petersen B E, Bowen W C, Patrene K D, Mars W M, Sullivan A K, Muras E N, Boggs S S,
Greenberger J S, Goff J P.
Bone marrow as a potential source of hepatic oval cells.
Science.
1999;
284
1168-1170
- 55
Eglitis M A, Mezey E.
Hematopoietic cells differentiate into both microglia and macroglia in the brains
of adult mice.
Proc Natl Acad Sci USA.
1997;
94
4080-4085
- 56
Mezey E, Chandross K J, Harta G, Maki R A, McKercher S R.
Turning blood into brain: cells bearing neuronal antigens generated in vivo from bone
marrow.
Science.
2000;
290
1779-1782
- 57
Orlic D, Kajstura J, Chimenti S, Jakoniuk I, Anderson S M, Li B, Pickel J, McKay R,
Nadal-Ginard B, Bodine D M, Leri A, Anversa P.
Bone marrow cells regenerate infarcted myocardium.
Nature.
2001;
410
701-705
- 58
Lagasse E, Connors H, Al-Dhalimy M, Reitsma M, Dohse M, Osborne L, Wang X, Finegold M,
Weissman I L, Grompe M.
Purified hematopoietic stem cells can differentiate into hepatocytes in vivo.
Nat Med.
2000;
6
1229-1234
- 59
Gleich O, Dooling R J, Presson J C.
Evidence for supporting cell proliferation and hair cell differentiation in the basilar
papilla of adult Belgian Waterslager canaries (Serinus canarius).
J Comp Neurol.
1997;
377
5-14
- 60
Stone J S, Rubel E W.
Cellular studies of auditory hair cell regeneration in birds.
Proc Natl Acad Sci USA.
2000;
97
11 714-11 721
- 61
Rivolta M N, Grix N, Lawlor P, Ashmore J F, Jagger D J, Holley M C.
Auditory hair cell precursors immortalized from the mammalian inner ear.
Proc R Soc Lond B Biol Sci.
1998;
265
1595-1603
- 62
Weir J, Rivolta M, Holley M.
Identification of differentiating cochlear hair cells in vitro.
Am J Otol.
2000;
21
130-134
- 63
Merlio J P, Ernfors P, Jaber M, Persson H.
Molecular cloning of rat trkC and distribution of cells expressing messenger RNAs
for members of the trk family in the rat central nervous system.
Neuroscience.
1992;
51
513-532
- 64
Pirvola U, Arumae U, Moshnyakov M, Palgi J, Saarma M, Ylikoski J.
Coordinated expression and function of neurotrophins and their receptors in the rat
inner ear during target innervation.
Hear Res.
1994;
75
131-144
- 65
Luo L, Koutnouyan H, Baird A, Ryan A F.
Acidic and basic FGF mRNA expression in the adult and developing rat cochlea.
Hear Res.
1993;
69
182-193
- 66
Ernfors P, Duan M L, ElShamy W M, Canlon B.
Protection of auditory neurons from aminoglycoside toxicity by neurotrophin-3.
Nat Med.
1996;
2
463-467
- 67
Staecker H, Kopke R, Malgrange B, Lefebvre P, van de Water T R.
NT-3 and/or BDNF therapy prevents loss of auditory neurons following loss of hair
cells.
Neuroreport.
1996;
7
889-894
- 68
Staecker H, Gabaizadeh R, Federoff H, van de Water T R.
Brain-derived neurotrophic factor gene therapy prevents spiral ganglion degeneration
after hair cell loss.
Otolaryngol Head Neck Surg.
1998;
119
7-13
- 69
Ernfors P, Lee K F, Kucera J, Jaenisch R.
Lack of neurotrophin-3 leads to deficiencies in the peripheral nervous system and
loss of limb proprioceptive afferents.
Cell.
1994;
77
503-512
- 70
Jones K R, Farinas I, Backus C, Reichardt L F.
Targeted disruption of the BDNF gene perturbs brain and sensory neuron development
but not motor neuron development.
Cell.
1994;
76
989-999
- 71
Dazert S, Baird A, Ryan A F.
Receptor-targeted delivery of an intracellular toxin to outer hair cells by fibroblast
growth factor.
Hear Res.
1998;
115
143-148
- 72
Low W, Dazert S, Baird A, Ryan A F.
Basic fibroblast growth factor (FGF-2) protects rat cochlear hair cells in organotypical
culture from aminoglycoside injury.
J Cell Physiol.
1996;
167
443-450
- 73
Pirvola U, Cao Y, Oellig C, Suoqiang Z, Pettersson R F, Ylikoski J.
The site of action of neuronal acidic fibroblast growth factor is the organ of Corti
of the rat cochlea.
Proc Natl Acad Sci USA.
1995;
92
9269-9273
- 74
Dazert S, Kim D, Luo L, Aletsee C, Garfunkel S, Maciag T, Baird A, Ryan A F.
Focal delivery of fibroblast growth factor-1 by transfected cells induces spiral ganglion
neurite targeting in vitro.
J Cell Physiol.
1998;
177
123-129
- 75
Woolf N K, Koehrn F J, Ryan A F.
Immunohistochemical localization of fibronectin-like protein in the inner ear of the
developing gerbil and rat.
Brain Res Dev Brain Res.
1992;
65
21-33
- 76
Whitlon D S, Zhang X, Kusakabe M.
Tenascin-C in the cochlea of the developing mouse.
J Comp Neurol.
1999;
406
361-374
- 77
Aletsee C, Mullen L, Kim D, Pak K, Brors D, Dazert S, Ryan A F.
The disintegrin kistrin inhibits neurite extension from spiral ganglion explants cultured
on laminin.
Audiol Neurootol.
2001;
6
57-65
- 78
Koppl C, Manley G A, Konishi M.
Auditory processing in birds.
Curr Opin Neurobiol.
2000;
10
474-481
- 79
Bermingham N A, Hassan B A, Price S D, Vollrath M A, Ben-Arie N, Eatock R A, Bellen H J,
Lysakowski A, Zoghbi H Y.
Math1: an essential gene for the generation of inner ear hair cells.
Science.
1999;
284
1837-1841
- 80
Zheng J L, Gao W Q.
Overexpression of Math1 induces robust production of extra hair cells in postnatal
rat inner ears.
Nat Neurosci.
2000;
3
580-586
- 81
Tsai H, Hardisty R E, Rhodes C, Kiernan A E, Roby P, Tymowska-Lalanne Z, Mburu P,
Rastan S, Hunter A J, Brown S D, Steel K P.
The mouse slalom mutant demonstrates a role for Jagged1 in neuroepithelial patterning
in the organ of Corti.
Hum Mol Genet.
2001;
10
507-512
- 82
McEvilly R J, Erkman L, Luo L, Sawchenko P E, Ryan A F, Rosenfeld M G.
Requirement for Brn-3.0 in differentiation and survival of sensory and motor neurons.
Nature.
1996;
384
574-577
- 83
Erkman L, McEvilly R J, Luo L, Ryan A K, Hooshmand F, O'Connell S M, Keithley E M,
Rapaport D H, Ryan A F, Rosenfeld M G.
Role of transcription factors Brn-3.1 and Brn-3.2 in auditory and visual system development.
Nature.
1996;
381
603-606
- 84
Vahava O, Morell R, Lynch E D, Weiss S, Kagan M E, Ahituv N, Morrow J E, Lee M K,
Skvorak A B, Morton C C, Blumenfeld A, Frydman M, Friedman T B, King M C, Avraham K B.
Mutation in transcription factor POU4F3 associated with inherited progressive hearing
loss in humans.
Science.
1998;
279
1950-1954
- 85
Pickles J O, van Heumen W R.
The expression of messenger RNAs coding for growth factors, their receptors, and eph-class
receptor tyrosine kinases in normal and ototoxically damaged chick cochleae.
Dev Neurosci.
1997;
19
476-487
- 86
Umemoto M, Sakagami M, Fukazawa K, Ashida K, Kubo T, Senda T, Yoneda Y.
Hair cell regeneration in the chick inner ear following acoustic trauma: ultrastructural
and immunohistochemical studies.
Cell Tissue Res.
1995;
281
435-443
- 87
Lee K H, Cotanche D A.
Potential role of bFGF and retinoic acid in the regeneration of chicken cochlear hair
cells.
Hear Res.
1996;
94
1-13
- 88
Lowenheim H, Furness D N, Kil J, Zinn C, Gultig K, Fero M L, Frost D, Gummer A W,
Roberts J M, Rubel E W, Hackney C M, Zenner H P.
Gene disruption of p27(Kip1) allows cell proliferation in the postnatal and adult
organ of corti.
Proc Natl Acad Sci USA.
1999;
96
4084-4088
- 89
Jordan C T, Lemischka I R.
Clonal and systemic analysis of long-term hematopoiesis in the mouse.
Genes & Development.
1990;
4
220-232
- 90
Wright D E, Cheshier S H, Wagers A J, Randall T D, Christensen J L, Weissman I L.
Cyclophosphamide/granulocyte colony-stimulating factor causes selective mobilization
of bone marrow hematopoietic stem cells into the blood after M phase of the cell cycle.
Blood.
2001;
97
2278-2285
- 91
Nishio N, Hisha H, Ogata H, Inaba M, Yamamoto Y, Amoh Y, Yasumizu R, Hanada K, Hamada H,
Ikehara S.
Changes in markers, receptors and adhesion molecules expressed on murine hemopoietic
stem cells after a single injection of 5- fluorouracil.
Stem Cells.
1996;
14
584-591
- 92
Campbell K H, McWhir J, W.A. R, Wilmut I.
Sheep cloned by nuclear transfer from a cultured cell line.
Nature.
1996;
380
64-66
- 93
Shamblott M J, Axelman J, Wang S, Bugg E M, Littlefield J W, Donovan P J, Blumenthal P D,
Huggins G R, Gearhart J D.
Derivation of pluripotent stem cells from cultured human primordial germ cells.
Proc Natl Acad Sci USA.
1998;
95
13 726-13 731
- 94
Wei G, Schubiger G, Harder F, Müller A M.
Stem cell plasticity in mammals and transdetermination in Drosophila: common themes?.
Stem Cells.
2000;
18
409-414
- 95
Kawagoe H, Humphries R K, Blair A, Sutherland H J, Hogge D E.
Expression of HOX genes, HOX cofactors, and MLL in phenotypically and functionally
defined subpopulations of leukemic and normal human hematopoietic cells.
Leukemia.
1999;
13
687-698
Priv.-Doz. Dr. Stefan Dazert
Hals-Nasen-Ohrenklinik der Ruhr-Universität Bochum · St. Elisabeth Hospital ·
Bleichstraße 15 · 44787 Bochum ·
Email: s.dazert@mail.uni-wuerzburg.de
