Abstract
A biologically monitored fractionation of the resinous exudate of Fabiana densa Remy var. ramulosa Wedd. led to the isolation of the two new diterpenes: ent-beyer-15-en-18-O-succinate and ent-beyer-15-en-18-O-oxalate as the unique compounds responsible for the observed antibacterial activity of this extract. Their structures were determined by 1D and 2D NMR spectroscopy.
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Silvia Erazo
Department of Pharmacological and Toxicological Chemistry
Faculty of Chemical and Pharmaceutical Sciences
University of Chile
P.O. Box 233, Santiago-1
Chile
Fax: +56-2-2227900
Email: serazo@uchile.cl