Synlett 2002(11): 1819-1822
DOI: 10.1055/s-2002-34887
LETTER
© Georg Thieme Verlag Stuttgart · New York

Baylis-Hillman Chemistry in Aqueous Media: A Fast and Practical Approach to the Azides of Baylis-Hillman Adducts in Solution and on Solid Phase [1]

A. Patra, A. K. Roy, S. Batra*, A. P. Bhaduri
Medicinal Chemistry Division, Central Drug Research Institute, Lucknow 226001, India
Fax: +91(522)223405; e-Mail: batra_san@yahoo.co.uk;
Further Information

Publication History

Received 9 September 2002
Publication Date:
21 October 2002 (online)

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Abstract

Fast and practical access to azides of Baylis-Hillman adducts, from the corresponding acetates in aqueous media and in excellent yields is described. The solution phase methodology has been successfully translated to the solid phase for applications toward combinatorial synthesis.

1

CDRI Communication no 6322.