An Enantiospecific Approach to 8,9-seco-C-Aromatic Taxanes

A.  Srikrishna; P.  Ravi Kumar; V.  Padmavathi

doi:10.1055/s-2002-34902

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An Enantiospecific Approach to 8,9-seco-C-Aromatic Taxanes

A. Srikrishna*, P. Ravi Kumar, V. Padmavathi
Department of Organic Chemistry, Indian Institute of Science, Bangalore 560 012, India.
Fax: +91(80)3600683; e-Mail: ask@orgchem.iisc.ernet.in);

Abstract

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Abstract

An enantiospecific approach to functionalised C-aromatic-8,9-seco-taxanes starting from the readily available monoterpene (R)-carvone is described.

Key words

C-aromatic-8,9-seco-taxanes - Paclitaxel - antitumor activity - carvone

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INSA Visiting Scientist. Present address: Department of Chemistry, Sri Venkateswara University, Tirupathi 517502, India.

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