Lithium Perchlorate Catalyzed Regioselective Ring Opening of Aziridines with Sodium Azide and Sodium Cyanide

Jhillu S.  Yadav; Basi V. Subba Reddy; G.  Parimala; P.  Venkatram Reddy

doi:10.1055/s-2002-35216

PAPER

Lithium Perchlorate Catalyzed Regioselective Ring Opening of Aziridines with Sodium Azide and Sodium Cyanide

Jhillu S. Yadav*, Basi V. Subba Reddy, G. Parimala, P. Venkatram Reddy
Organic Chemistry Division-I, Indian Institute of Chemical Technology, Hyderabad 500 007, India
Fax: +91(40)7160512; e-Mail: yadav@iict.ap.nic.in;

Abstract

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Abstract

Aziridines react smoothly with sodium azide and sodium cyanide in the presence of catalytic amount of lithium perchlorate under essentially mild and neutral reaction conditions to afford the corresponding β-azido and β-cyanoamines in high yields with high regioselectivity.

Keywords

lithium perchlorate - aziridines - regioselective - β-azidoamines

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References

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