5-Hydroxyramulosin, a New Natural Product Produced by Phoma tropica, a Marine-Derived Fungus Isolated from the Alga Fucus spiralis

Abstract

The fungus Phoma tropica was isolated from the inner tissue of the marine brown alga Fucus spiralis. After large-scale cultivation the fungus was investigated for its secondary metabolite content and found to contain the new natural product 5-hydroxyramulosin (1) together with 7-methoxycoumarin. Both structures were elucidated using spectroscopic methods, mainly 1D and 2D NMR, and in the case of 1, a single crystal X-ray diffraction analysis.

References

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