Semin Musculoskelet Radiol 2002; 06(3): 197-206
DOI: 10.1055/s-2002-36717
Copyright © 2002 by Thieme Medical Publishers, Inc., 333 Seventh Avenue, New York, NY 10001, USA. Tel.: +1(212) 584-4662

Radiology of Osteoporosis

Swee-Tian Quek1 , Wilfred C.G. Peh2
  • 1Department of Diagnostic Imaging, National Cancer Centre Singapore, Singapore
  • 2Department of Diagnostic Radiology, Singapore General Hospital, Singapore
Further Information

Publication History

Publication Date:
23 January 2003 (online)

ABSTRACT

Osteoporosis is a common metabolic bone disorder that may be broadly subdivided into generalized or regional osteoporosis. This article reviews the common causes of generalized osteoporosis with emphasis on the radiological appearances, complications, and differential diagnosis. The more important causes of regional osteoporosis such as disuse osteoporosis, reflex sympathetic dystrophy, and transient regional osteoporosis are also discussed, and their imaging features are reviewed.

REFERENCES

  • 1 Thompson Jr C R. Heparin osteoporosis. An experimental model using rats.  J Bone Joint Surg Am . 1973;  55 606-162
  • 2 Singh M, Nagrath A R, Maini P S. Changes in trabecular pattern of the upper end of the femur as an index of osteoporosis.  J Bone Joint Surg Am . 1970;  52 457-467
  • 3 Harris W H, Heaney R P. Skeletal renewal and metabolic bone disease.  N Engl J Med . 1969;  280 303-311
  • 4 Ardran G M. Bone destruction not demonstrable by radiography.  Br J Radiol . 1951;  24 107-115
  • 5 Guglielmi G, Gluer C C, Majumdar S. Current methods and advances in bone densitometry.  Eur Radiol . 1995;  5 129-139
  • 6 Yagan R, Radivoyevitch M, Khan M A. Double cortical line in the acetabular roof: a sign of disuse osteoporosis.  Radiology . 1987;  165 171-175
  • 7 Mayo-Smith W, Rosenthal D I. Radiographic appearance of osteopenia.  Radiol Clin North Am . 1991;  29 37-47
  • 8 De Smet A A, Robinson R G, Johnson B E. Spinal compression fractures in osteoporotic women: patterns and relationship to hyperkyphosis.  Radiology . 1988;  166 497-500
  • 9 Mitchell D C. Fractures in brittle bone diseases.  Orthop Clin North Am . 1972;  3 787-792
  • 10 Parfitt A M. Trabecular bone architecture in the pathogenesis and prevention of fracture.  Am J Med . 1987;  82 68-72
  • 11 Davies A M, Evans N S, Struthers G R. Parasymphyseal and associated insufficiency fractures of the pelvis and sacrum.  Br J Radiol . 1988;  61 103-108
  • 12 Hauge M D, Cooper K L, Litin S C. Insufficiency fractures of the pelvis that simulate metastatic disease.  Mayo Clin Proc . 1988;  63 807-812
  • 13 Schneider R, Yacovone J, Ghelman B. Unsuspected sacral fractures: detection by radionuclide bone scanning.  Am J Roentgenol . 1985;  144 337-341
  • 14 Balseiro J, Brower A C, Ziessman H A. Scintigraphic diagnosis of sacral fractures.  Am J Roentgenol . 1987;  148 111-113
  • 15 Peh W CG, Khong P L, Yin Y. Imaging of pelvic insufficiency fractures.  RadioGraphics . 1996;  16 335-348
  • 16 Brahme S K, Cervilla V, Vint V. Magnetic resonance appearance of sacral insufficiency fractures.  Skeletal Radiol . 1990;  19 489-493
  • 17 Blomlie V, Lien H H, Iversen T. Radiation-induced insufficiency fractures of the sacrum: evaluation with MR imaging.  Radiology . 1993;  188 241-244
  • 18 Peh W CG, Cheng K C, Ho W Y. Transient bone marrow oedema: a variant pattern of sacral insufficiency fractures.  Australas Radiol . 1998;  42 102-105
  • 19 Peh W CG. Intrafracture fluid: a new diagnostic sign of insufficiency fractures of the sacrum and ilium.  Br J Radiol . 2000;  73 895-898
  • 20 Seo G S, Aoki J, Karakida O. Ischiopubic insufficiency fractures: MRI appearances.  Skeletal Radiol . 1997;  26 705-710
  • 21 Arnstein A R. Regional osteoporosis.  Orthop Clin North Am . 1972;  3 585-600
  • 22 Jones G. Radiological appearance of disuse osteoporosis.  Clin Radiol . 1969;  20 345-353
  • 23 Jaworski Z F, Uhthoff H K. Reversibility of nontraumatic disuse osteoporosis during its active phase.  Bone . 1986;  7 431-439
  • 24 Joyce J M, Keats T E. Disuse osteoporosis: mimic of neoplastic disease.  Skeletal Radiol . 1986;  15 129-132
  • 25 Sarangi P P, Ward A J, Smith E J. Algodystrophy and osteoporosis after tibial fractures.  J Bone Joint Surg Br . 1993;  75 450-452
  • 26 Schwartzman R J, McLellan T L. Reflex sympathetic dystrophy. A review.  Arch Neurol . 1987;  44 555-561
  • 27 Schiffenbauer J, Fagien M. Reflex sympathetic dystrophy involving multiple extremities.  J Rheumatol . 1993;  20 165-169
  • 28 Resnick D, Niwayama G. Osteoporosis. In: Resnick D, ed. Diagnosis of Bone and Joint Disorders 3rd ed. Philadelphia: WB Saunders 1995: 1783-1853
  • 29 Constantinesco A, Brunot B, Demangeat J L. Three phase bone scanning as an aid to early diagnosis in reflex sympathetic dystrophy of the hand. A study of eighty-nine cases.  Ann Chir Main . 1986;  5 93-104
  • 30 Zyluk A. The usefulness of quantitative evaluation of three-phase scintigraphy in the diagnosis of post-traumatic reflex sympathetic dystrophy.  J Hand Surg Br . 1999;  24 16-21
  • 31 Kozin F, Soin J S, Ryan L M. Bone scintigraphy in the reflex sympathetic dystrophy syndrome.  Radiology . 1981;  138 437-443
  • 32 Koch E, Hofer H O, Sialer G. Failure of MR imaging to detect reflex sympathetic dystrophy of the extremities.  Am J Roentgenol . 1991;  156 113-115
  • 33 Schweitzer M E, Mandel S, Schwartzman R J. Reflex sympathetic dystrophy revisited: MR imaging findings before and after infusion of contrast material.  Radiology . 1995;  195 211-214
  • 34 Borre G E, Borre D G, Hofer B. Sudeck's dystrophy of the hand. MR imaging.  Clin Imaging . 1995;  19 188-192
  • 35 Wuisman P I, Noorda R J. Transient osteoporosis of the hip.  J Bone Joint Surg Br . 1998;  80 743
  • 36 Koski J M, Mullykangas-Luosujarvi R. Transient osteoporosis of the hip with joint effusion detected by ultrasonography.  Clin Rheumatol . 1997;  16 404-408
  • 37 Duncan H, Frame B, Frost H M, Arnstein A R. Migratory osteolysis of the lower extremities.  Ann Intern Med . 1967;  66 1165-1173
  • 38 Steiner R M, McKeever C. Regional migratory osteoporosis.  J Can Assoc Radiol . 1973;  24 70-75
  • 39 Banas M P, Kaplan F S, Fallon M D. Regional migratory osteoporosis. A case report and review of the literature.  Clin Orthop . 1990;  250 303-309
  • 40 Mavichak V, Murray T M, Hodsman A B. Regional migratory osteoporosis of the lower extremities with vertebral osteoporosis.  Bone . 1986;  7 343-349
  • 41 Shier C K, Ellis B I, Kleerekoper M. Disseminated migratory osteoporosis: an unusual pattern of osteoporosis.  J Can Assoc Radiol . 1987;  38 56-59
  • 42 Schils J, Piraino D, Richmond B J. Transient osteoporosis of the hip: clinical and imaging features.  Cleve Clin J Med . 1992;  59 483-488
  • 43 Potter H, Moran M, Schneider R. Magnetic resonance imaging in diagnosis of transient osteoporosis of the hip.  Clin Orthop . 1992;  280 223-229
  • 44 Tannenbaum H, Esdaile J, Rosenthall L. Joint imaging in regional migratory osteoporosis.  J Rheumatol . 1980;  7 237-244
  • 45 Beltran J, Noto A M, McGhee R B. Infections of the musculoskeletal system: high-field-strength MR imaging.  Radiology . 1987;  164 449-454
  • 46 Bloem J L. Transient osteoporosis of the hip: MR imaging.  Radiology . 1988;  167 753-755