Synthesis, Table of Contents SHORTPAPER © Georg Thieme Verlag Stuttgart · New York A Direct Introduction of the Mercaptoacetic Acid Unit into Amino Acid Esters George A. Kraus*, Jaehoon Bae, Prabir K. ChoudhuryDepartment of Chemistry, Iowa State University, Ames, IA 50011, USAFax: +1(515)2940105; e-Mail: gakraus@iastate.edu; Recommend Article Abstract Buy Article All articles of this category Abstract The reaction of amino acid esters with 1,3-oxathiolan-5-one 1a provided thiol amides 3. Key words combinatorial chemistry - amino acids - amines - ligands - thiols - acylations - esters Full Text References References 1a Baidoo KE. Lever SZ. Bioconjugate Chem. 1990, 1: 132 1b Bryson N. Dewan JC. Lister-James J. Jones AG. Davison A. Inorg. Chem. 1988, 27: 2154 2 Bell RA. Dickson KC. Valliant JF. Can. J. Chem. 1999, 77: 146 3 Higashiya S. Narizuka S. Konno A. Maeda T. Momota K. Fuchigami T. J. Org. Chem. 1999, 64: 133 4 Molt KR, Hechenbleikner I, and Homberg O. inventors; A U.S. 3305573. The diphenylsilyl analog has been reported: 5a Compound 3a: Johannsen B. Noll B. Leibnitz G. Reck G. Noll St. Spies H. Radiochim. Acta 1993, 63: 133 5b Compound 3d: Davidovich YA. Semenova NN. Babievskii KK. Rogozhin SV. Izv. Akad. Nauk., Ser. Khim. 1986, 2139 6 MTPA ester: Dale JA. Mosher HS. J. Am. Chem. Soc. 1973, 95: 512
