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Dtsch Med Wochenschr 2003; 128(6): 281-287
DOI: 10.1055/s-2003-37078
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© Georg Thieme Verlag Stuttgart · New York

Bedeutung von GP IIb/IIIa-Rezeptor-Antagonisten in der invasiven Kardiologie

Impact of GP IIb/IIIa antagonists in interventional cardiologyB. Scheller1 , B. Hennen1 , M. Böhm1 , G. Nickenig1
  • 1Innere Medizin III, Kardiologie/Angiologie, (Direktor: Prof. Dr. M. Böhm), Universität des Saarlandes, Homburg/Saar
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Publication History

eingereicht: 6.5.2002

akzeptiert: 22.9.2002

Publication Date:
06 February 2003 (online)

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Neben der ursprünglichen atherosklerotischen Gefäßwandläsion spielen Thrombozyten bei der Atherogenese, aber insbesondere beim akuten Koronarsyndrom (ACS) eine zentrale Rolle [18]. GP IIb/IIIa-Antagonisten hemmen die gemeinsame Endstrecke in der Thrombozytenaggregation. Eine Vielzahl von Untersuchungen zeigen eine Reduktion kardialer Ereignisse durch GP IIb/IIIa-Antagonisten. Aufgrund des unterschiedlichen Studienaufbaus und der unterschiedlichen untersuchten Patientengruppen besteht eine Restunsicherheit zu der Frage, zu welchem Zeitpunkt und in welcher definierten klinischen Situation ein GP IIb/IIIa-Antagonist verabreicht werden sollte.

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Dr. med. Bruno Scheller

Innere Medizin III, Universitätskliniken des Saarlandes

66421 Homburg/Saar

Phone: +49/6841/1623350

Fax: +49/6841/1623596

Email: bruno.scheller@uniklinik-saarland.de