Chronic Thromboembolic Pulmonary Hypertension

Peter F. Fedullo; William R. Auger; Kim M. Kerr; Nick H. Kim

doi:10.1055/s-2003-41088

Seminars in Respiratory and Critical Care Medicine, Table of Contents

Semin Respir Crit Care Med 2003; 24(3): 273-286
DOI: 10.1055/s-2003-41088

Chronic Thromboembolic Pulmonary Hypertension

Peter F. Fedullo, William R. Auger, Kim M. Kerr, Nick H. Kim

Pulmonary and Critical Care Division, University of California, San Diego, UCSD Medical Center, San Diego, California

Abstract

ABSTRACT

Over the past 4 decades, chronic thromboembolic pulmonary hypertension has evolved from an autopsy curiosity to a potentially correctable form of pulmonary hypertension. Approximately 2500 thromboendarterectomy procedures have now been performed worldwide with mortality rates reported by established programs experienced in the management of this disease process falling to a range of 4 to 8%. Following a successful pulmonary thromboendarterectomy, substantial improvement, and at times normalization, can be achieved in right ventricular function, gas exchange, exercise capacity, and quality of life. Reperfusion lung injury and residual postoperative pulmonary hypertension remain the major causes of mortality in patients undergoing the procedure.

KEYWORDS

Pulmonary hypertension - thromboembolism - pulmonary embolism - pulmonary thromboendarterectomy - chronic thromboembolic pulmonary hypertension

Full Text

References

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