Available scientific data and considerable clinical experience indicate that over
95 % of colorectal cancers arise in benign adenomatous polyps that develop and advance
very slowly over many years. Interruption of this adenoma–carcinoma sequence by finding
and resecting polyps is a highly effective method of preventing colorectal cancer.
Colonoscopy is the procedure of choice for both the diagnosis and resection of colorectal
polyps. Patients who have had colonoscopic resection of adenomas, and in some cases
their close relatives, are at a higher than average risk for developing future polyps
and cancer, and likely will benefit from periodic follow-up colonoscopic surveillance.
This surveillance should to be tailored to the perceived risk of each individual case
depending on the features of the resected adenomas and other patient factors such
as family history. Widespread adoption of current polyp guideline recommendations
would be highly protective and yet would conserve medical resources.
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Prof. J. H. Bond, M. D.
Gastroenterology Section (111D) · VA Medical Center
One Veterans Drive · Minneapolis · MN 554l7 · USA
Fax: +1-612-725-2248
Email: john.bond@med.va.gov