Synthesis 2003(16): 2503-2506  
DOI: 10.1055/s-2003-42436
PAPER
© Georg Thieme Verlag Stuttgart · New York

Scandium(III) Triflate as an Efficient and Recyclable Catalyst for Chemo­selective Conversion of Carbonyl Compounds to 1,3-Oxathiolanes

Babak Karimi*, Leila Ma’mani
Department of Chemistry, Institute for Advanced Studies in Basic Sciences (IASBS), P. O. Box 45195-159, Gava Zang, Zanjan, Iran
Further Information

Publication History

Received 17 March 2003
Publication Date:
23 October 2003 (online)

Abstract

A variety of carbonyl compounds can be easily and rapidly converted to the corresponding 1,3-oxathiolanes in the presence of a catalytic amount of scandium(III) triflate [Sc(OTf)3] in CH2Cl2. After completion of the reaction, the catalyst can straightforwardly be recovered using standard methods. Moreover, by employing this protocol, chemoselective oxathioacetalization of aldehydes in the presence of ketones can be achieved.