Flavonoids and Coumarins from Leaves of Phellodendron chinense

Abstract

Three new compounds, phellodensin G, phellodenols D and E have been isolated from the leaves of Phellodendron chinense Schneid (Rutaceae), together with thirteen known compounds. Their structures were established by means of spectroscopic analysis, including extensive 2D NMR and mass spectra.

References

• 1 Shiao P G. Photocatalogue of Chinese traditional medicine. Taiwan Business Publication Company Taipei; 1989 Vol. 3: p. 86
• 2 Gray A I, Bhandari P, Waterman P G. New protolimonoids from the fruits of Phellodendron chinense .  Phytochemistry. 1988;  27 1805-8
• 3 Zhong Yao Z hi. Institute of Medicinal Plant Sources Discovery, Chinese Academy of Medical Science, ed. People’s Health Publication Beijing; 1994; Vol. 5: p. 550
• 4 Mabry T J, Markham K R, Thomas M B. The systematic identification of flavonoids. Springer Verlag New York; 1970: p. 44
• 5 Kuroyanagi M, Arakawa T, Hirayama Y, Hayashi T. Antibacterial and antiandrogen flavonoids from Sophora flavescens .  Journal of Natural Products. 1999;  62 1595-9
• 6 Wu T S, Hsu M Y, Damu A G, Kuo P C, Su C R, Li C Y, Sun H D. Constituents of leaves of Phellodendron chinense var. glabriusculum .  Heterocycles. 2003;  60 397-404
• 7 Ingham J L, Tahara S, Dziedzic S Z. New 3-hydroxyflavanone (dihydroflavonol) phytoalexins from the papilionate legume Shuteria vestita .  Journal of Natural Products. 1986;  49 631-8
• 8 Colombain M, Girard C, Muyard F, Bevalot F, Tillequin F, Waterman P G. Eight new prenylcoumarins from Phebalium clavatum .  Journal of Natural Products. 2002;  65 458-61
• 9 Cheng M J, Yang C H, Lin W Y, Lin W Y, Tsai I L, Chen I S. Chemical constituents from the leaves of Zanthoxylum schinifolium .  Journal of the Chinese Chemical Society. 2002;  49 125-8
• 10 Rahman A U, Begum S, Saied S, Choudhary M I, Akhtar F. A steroidal glycoside from Clerodendron inerme .  Phytochemistry. 1997;  45 1721-2
• 11 Nakatani Y, Ourisson G, Beck J P. Chemistry and biochemistry of Chinese drugs. VII cytostatic pheophytins from silkworm excreta and derived photocytotoxic pheophorbides.  Chemical & Pharmaceutical Bulletin. 1981;  29 2261-9
• 12 Burke B A, Parkins H. Coumarins from Amyris balsamifera .  Phytochemistry. 1978;  13 1073-5
• 13 Calis I, Tasdemir D, Sticher O, Nishibe S. Phenylethanoid glycosides from Digitalis ferruginea subsp. ferruginea ( = D. aurea Lindley) (Scrophulariaceae).  Chemical & Pharmaceutical Bulletin. 1999;  47 1305-7