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Synthesis 2004(4): 501-502  
DOI: 10.1055/s-2004-815946
SHORTPAPER
© Georg Thieme Verlag Stuttgart · New York

Highly Efficient Regioselective Ring Opening of Aziridines to β-Haloamines in the Presence of β-Cyclodextrin in Water

N. Srilakshmi Krishnaveni, K. Surendra, M. Narender, Y. V. D. Nageswar, K. Rama Rao*
Organic Chemistry Division-I, Indian Institute of Chemical Technology, Hyderabad-500 007, India
e-Mail: ramaraok@iict.res.in;
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Publication History

Received 14 October 2003
Publication Date:
03 February 2004 (online)

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Abstract

Aziridines are opened regioselectively with hydrogen and lithium halides to yield β-haloamines in the presence of β-cyclodextrin using water as the solvent.

Key words

aziridines - hydrogen halides - lithium halides - β-haloamines - β-cyclodextrin - water