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Synthesis 2004(6): 923-927
DOI: 10.1055/s-2004-815996
DOI: 10.1055/s-2004-815996
PAPER
© Georg Thieme Verlag Stuttgart · New York
P-BEMP: A New Efficient and Commercially Available User-Friendly and Recyclable Heterogeneous Organocatalyst for the Michael Addition of 1,3-Dicarbonyl Compounds
Further Information
Received
23 October 2003
Publication Date:
04 March 2004 (online)
Publication History
Publication Date:
04 March 2004 (online)
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Abstract
Michael addition of 1,3-dicarbonyls with various Michael acceptors has been found to be catalyzed by commercially available, user-friendly and recyclable N-phenyl-tris(di-methylamino)iminophosphorane immobilized on polystyrene resin (P-BEMP). The reaction does not require anhydrous solvents or inert atmosphere and proceeds smoothly at room temperature leading to the corresponding adducts, which can be conveniently isolated in high yield and with high chemical purity by simple filtration.
Key words
1,3-dicarbonyls - heterogeneous catalysis - Michael addition - polymer supported iminophosphoranes
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References
After the first reaction the color of the catalyst changed from yellow to brown, but this modification remains insensitive towards the catalytic activity.