Int J Sports Med 2004; 25(6): 450-456
DOI: 10.1055/s-2004-820939
Physiology & Biochemistry

© Georg Thieme Verlag KG Stuttgart · New York

Fatigue and Recovery After High-Intensity Exercise Part I: Neuromuscular Fatigue

G. Lattier1 , G. Y. Millet1 , A. Martin1 , V. Martin1
  • 1Faculty of Sport Sciences, University of Burgundy, Dijon, France
Further Information

Publication History

Accepted after revision: October 15, 2003

Publication Date:
02 September 2004 (online)

Abstract

The contribution of central and peripheral factors to muscle fatigue were quantified following a high-intensity uphill running exercise. Eight male volunteers performed an intermittent exercise at 120 % of maximal aerobic speed on a treadmill with an 18 % grade. Electrically evoked and voluntary contractions of the knee extensors and EMG of the two vastii were analyzed before and immediately after the high-intensity exercise. Isometric maximal voluntary contraction decreased slightly (- 7 ± 8 %; p < 0.05) after exercise but no changes were found in the level of maximal activation or in the torque produced by a 80 Hz maximal stimulation applied to the femoral nerve. Following exercise, the single twitch was characterized by lower peak torque, maximal rate of force development, and relaxation (- 28 ± 11 %, - 25 ± 12 %, - 31 ± 15 % respectively, p < 0.001), and higher surface of the M-wave for both vastii. The ratio between the torques evoked by 20 Hz and 80 Hz stimulation declined significantly (- 22 ± 10 %, p < 0.01) after exercise. These findings indicate that muscle fatigue after high-intensity running exercise is due to significant alteration in excitation-contraction coupling and that this type of exercise does not induce significant central fatigue or changes at the crossbridge level.

References

  • 1 Allen D G, Lannergren J, Westerblad H. Muscle cell function during prolonged activity: cellular mechanisms of fatigue.  Exp Physiol. 1995;  80 497-527
  • 2 Allen D G, Westerblad H. Role of phosphate and calcium stores in muscle fatigue.  J Physiol. 2001;  536 657-665
  • 3 Behm D G, St-Pierre D M. Effects of fatigue duration and muscle type on voluntary and evoked contractile properties.  J Appl Physiol. 1997;  82 1654-1661
  • 4 Bentley D J, Smith P A, Davie A J, Zhou S. Muscle activation of the knee extensors following high intensity endurance exercise in cyclists.  Eur J Appl Physiol. 2000;  81 297-302
  • 5 Bruton J D, Lannergren J, Westerblad H. Mechano-sensitive linkage in excitation-contraction coupling in frog skeletal muscle.  J Physiol. 1995;  484 737-742
  • 6 Dutka T L, Lamb G D. Effect of lactate on depolarization-induced Ca(2 +) release in mechanically skinned skeletal muscle fibers.  Am J Physiol. 2000;  278 517-525
  • 7 Ebenbichler G, Kollmitzer J, Quittan M, Uhl F, Kirtley C, Fialka V. EMG fatigue patterns accompanying isometric fatiguing knee-extensions are different in mono- and bi-articular muscles.  Electroencephalogr Clin Neurophysiol. 1998;  109 256-262
  • 8 Fitts R H. Cellular mechanisms of muscle fatigue.  Physiol Rev. 1994;  74 49-94
  • 9 Fryer M W, Owen V J, Lamb G D, Stephenson D G. Effects of creatine phosphate and P(i) on Ca2 + movements and tension development in rat skinned skeletal muscle fibres.  J Physiol. 1995;  482 123-140
  • 10 Gandevia S C. Spinal and supraspinal factors in human muscle fatigue.  Physiol Rev. 2001;  81 1725-1789
  • 11 Garland S J. Role of small diameter afferents in reflex inhibition during human muscle fatigue.  J Physiol. 1991;  435 547-558
  • 12 Huang W H, Askari A. Regulation of (Na++K+)-ATPase by inorganic phosphate: pH dependence and physiological implications.  Biochem Biophys Res Commun. 1984;  123 438-443
  • 13 Hunter A M, St Clair Gibson A, Mbambo Z, Lambert M I, Noakes T D. The effects of heat stress on neuromuscular activity during endurance exercise.  Pflugers Arch. 2002;  444 738-743
  • 14 Jones D A. High- and low-frequency fatigue revisited.  Acta Physiol Scand. 1996;  156 265-270
  • 15 Kenny G P, Niedre P C. The effect of exercise intensity on the post-exercise esophageal temperature response.  Eur J Appl Physiol. 2002;  86 342-346
  • 16 Kent-Braun J A. Central and peripheral contributions to muscle fatigue in humans during sustained maximal effort.  Eur J Appl Physiol. 1999;  80 57-63
  • 17 Kukulka C G, Clamann H P. Comparison of the recruitment and discharge properties of motor units in human brachial biceps and adductor pollicis during isometric contractions.  Brain Res. 1981;  219 45-55
  • 18 Lattier G, Millet G Y, Martin A, Martin V. Fatigue and recovery after high intensity exercise. Part II: Recovery interventions.  Int J Sports Med. 2004;  in press
  • 19 Metzger J M, Moss R L. Greater hydrogen ion-induced depression of tension and velocity in skinned single fibres of rat fast than slow muscles.  J Physiol. 1987;  393 727-742
  • 20 Miller R G, Giannini D, Milner-Brown H S, Layzer R B, Koretsky A P, Hooper D, Weiner M W. Effects of fatiguing exercise on high-energy phosphates, force, and EMG: evidence for three phases of recovery.  Muscle Nerve. 1987;  10 810-821
  • 21 Newham D J, Mills K R, Quigley B M, Edwards R HT. Pain and fatigue after concentric and eccentric muscle contractions.  Clin Science. 1983;  64 55-62
  • 22 Nielsen O B, de Paoli F, Overgaard K. Protective effects of lactic acid on force production in rat skeletal muscle.  J Physiol. 2001;  536 161-166
  • 23 Rotto D M, Kaufman M P. Effect of metabolic products of muscular contraction on discharge of group III and IV afferents.  J Appl Physiol. 1988;  64 2306-2313
  • 24 Sahlin K, Ren J M. Relationship of contraction capacity to metabolic changes during recovery from a fatiguing contraction.  J Appl Physiol. 1989;  67 648-654
  • 25 Sjogaard G, Adams R P, Saltin B. Water and ion shifts in skeletal muscle of humans with intense dynamic knee extension.  Am J Physiol. 1985;  248 190-196
  • 26 Sloniger M A, Cureton K J, Prior B M, Evans E M. Lower extremity muscle activation during horizontal and uphill running.  J Appl Physiol. 1997;  83 2073-2079
  • 27 Stackhouse S K, Reisman D S, Binder-Macleod S A. Challenging the role of pH in skeletal muscle fatigue.  Phys Ther. 2001;  81 1897-1903
  • 28 Strojnik V, Komi P V. Fatigue after submaximal intensive stretch-shortening cycle exercise.  Med Sci Sports Exerc. 2000;  32 1314-1319
  • 29 Warren G L, Ingalls C P, Lowe D A, Armstrong R B. Excitation-contraction uncoupling: major role in contraction-induced muscle injury.  Exerc Sport Sci Rev. 2001;  29 82-87
  • 30 West W, Hicks A, McKelvie R, O'Brien J. The relationship between plasma potassium, muscle membrane excitability and force following quadriceps fatigue.  Pflugers Arch. 1996;  432 43-49

G. Lattier

Faculty of Sports Sciences · University of Burgundy

BP 27877

21078 Dijon Cedex

France

Phone: + 33380396762

Fax: + 33 3 80 39 67 02

Email: Gregory.Lattier@u-bourgogne.fr