Subscribe to RSS
DOI: 10.1055/s-2004-822852
Copyright © 2004 by Thieme Medical Publishers, Inc., 333 Seventh Avenue, New York, NY 10001, USA.
Improvement in Obstructive Sleep Apnea in the Supine “Knees-Up” Position
Publication History
Publication Date:
17 March 2004 (online)

We report a 38-year-old man with obstructive sleep apnea whose sleep-disordered breathing was substantially reduced by sleep in the supine, “knees-up” position, relative to his sleep in the customary supine, “knees-down” position. No obvious anatomic or pathophysiologic alterations explained this phenomenon. The effect was reproducible in the patient 4 years later. Potential mechanisms underlying such improvement, including alterations in upper airway/lung volume dependence and venous supply to upper airway vasculature, are discussed. This manipulation could be an important adjunctive treatment for a subset of obstructive sleep apnea patients demonstrating such an effect.
KEYWORDS
Obstructive sleep apnea - body position - sleep-disordered breathing
REFERENCES
- 1 Cartwright R D, Diaz F, Lloyd S. The effects of sleep posture and sleep stage on apnea frequency. Sleep. 1991; 14 351-353
- 2 Oksenberg A, Silverberg D S, Arons E et al.. Positional vs nonpositional obstructive sleep apnea patients: anthropomorphic, nocturnal polysomnographic, and multiple sleep latency data. Chest. 1997; 112 629-639
- 3 Pevernagie D A, Stanson A W, Sheedy II P F et al.. Effects of body position on the upper airway of patients with obstructive sleep apnea. Am J Respir Crit Care Med. 1995; 152 179-185
- 4 Taber C W. Taber's Cyclopedic Medical Dictionary Including a Digest of Medical Subjects: Medicine, Surgery, Nursing, Dietetics, Physical Therapy. 6th ed. Philadelphia, PA; FA Davis Co 1955: D40
- 5 Boren H G, Kory R C, Syner J C. The Veterans Administration-Army cooperative study of pulmonary function: II. The lung volume and its subdivisions in normal men. Am J Med. 1966; 41 96-114
- 6 Craig Jr A B. Effects of position on expiratory reserve volume of the lungs. J Appl Physiol. 1960; 15 59-61
- 7 Hoffstein V, Zamel N, Phillipson E A. Lung volume dependence of pharyngeal cross-sectional area in patients with obstructive sleep apnea. Am Rev Respir Dis. 1984; 130 175-178
- 8 Series F, Cormier Y, Lampron N et al.. Influence of lung volume in sleep apnoea. Thorax. 1989; 44 52-57
- 9 Series F, Marc I. Influence of lung volume dependence of upper airway resistance during continuous negative airway pressure. J Appl Physiol. 1994; 77 840-844
- 10 Shepard Jr J W, Pevernagie D A, Stanson A W et al.. Effects of changes in central venous pressure on upper airway size in patients with obstructive sleep apnea. Am J Respir Crit Care Med. 1996; 153 250-254
- 11 Oksenberg A, Silverberg D S, Arons E et al.. The sleep supine position has a major effect on optimal nasal continuous positive airway pressure: relationship with rapid eye movements and non-rapid eye movements sleep, body mass index, respiratory disturbance index, and age. Chest. 1999; 116 1000-1006
Donald L BliwisePh.D.
Wesley Woods Hospital, Emory University Medical School
1821 Clifton Rd. NE
Atlanta, GA 30329
Email: dbliwis@emory.edu