Subscribe to RSS
Please copy the URL and add it into your RSS Feed Reader.
https://www.thieme-connect.de/rss/thieme/en/10.1055-s-00000009.xml
Am J Perinatol 2004; 21(3): 167-172
DOI: 10.1055/s-2004-823772
DOI: 10.1055/s-2004-823772
Preterm Brain Injury: Imaging and Neurodevelopmental Outcome
Further Information
Publication History
Publication Date:
14 April 2004 (online)
Although neonatal survival has dramatically improved during the last decade, there remain a significant number of infants who sustain brain injury and exhibit developmental delay. This review identifies the current modes of brain imaging available to the neonatologist and the correlation between neonatal imaging and clinical outcomes to facilitate early identification of these at-risk newborns.
KEYWORDS
Neurodevelopment - cranial ultrasound - magnetic resonance imaging
REFERENCES
- 1 McCormick M C, Richardson D K. Premature infants grow up. N Engl J Med. 2002; 346 197-198
- 2 Perspectives in disease prevention and health promotion years of potential life lost attributable to low birthweight-United States, 1980 birth cohort. MMWR Morb Mortal Wkly Rep. 1986; 35 188-190
- 3 Volpe J J. Neurobiology of periventricular leukomalacia in the premature infant. Pediatr Res. 2001; 50 553-562
- 4 Pinto-Martin J A, Riolo S, Cnaan A, Holzman C, Susser M W, Paneth N. Cranial ultrasound prediction of disabling and non-disabling cerebral palsy at age two in a LBW population. Pediatrics. 1995; 95 249-254
- 5 Whitaker A H, Feldman J F, Rossem R V et al.. Neonatal cranial ultrasound abnormalities in LBW infants: relation to cognitive outcomes at six years of age. Pediatrics. 1996; 98 719-729
- 6 Paneth N. Classifying brain damage in preterm infants. J Pediatr. 1999; 134 527-528
- 7 Inder T, Huppi P S, Zienatara G P et al.. Early detection of PVL by diffusion-weighted magnetic resonance imaging techniques. J Pediatr. 1999; 134 631-634
- 8 Maalouf E F, Duggan P J, Rutherford M A et al.. Magnetic resonance imaging of the brain in a cohort of extremely preterm infants. J Pediatr. 1999; 135 351-357
- 9 Hoon Jr A H, Melham E R. Neuroimaging: application in disorders of early brain development. J Dev Behav Pediatr. 2000; 21 291-302
- 10 Ment L R, Vohr B, Allan W et al.. The etiology and outcome of cerebral ventriculomegaly at term in very low birth weight preterm infants. Pediatrics. 1999; 104(2 pt 1) 243-248
- 11 Maalouf E F, Duggan P J, Counsell S J et al.. Comparison of findings on cranial ultrasound and magnetic resonance imaging in preterm infants. Pediatrics. 2001; 107 719-727
- 12 Pinto-Martin J A, Whitaker A H, Feldman J F, Rossem R V, Paneth N. Relation of cranial ultrasound abnormalities in low-birthweight infants to motor or cognitive performance at ages 2, 6, and 9 years. Dev Med Child Neurol. 1999; 41 826-833
- 13 Goetz M C, Gretebeck R J, Oh K S, Shaffer D, Hermansen M C. Incidence, timing, and follow-up of periventricular leukomalacia. Am J Perinatol. 1995; 12 325-327
- 14 Vohr B R, Allan W C, Westerveld M et al.. School-age outcomes of very low birth weight infants in the indomethacin intraventricular hemorrhage prevention trial. Pediatrics. 2003; 111(4 pt 1) e340-e346
- 15 van Wezel-Meijler G, van der Knaap M S, Oosting J et al.. Predictive value of neonatal MRI as compared to ultrasound in premature infants with mild periventricular white matter changes. Neuropediatrics. 1999; 30 231-238
- 16 De Vries L S, Regev R, Pennock L M et al.. Ultrasound evolution and later outcome of infants with periventricular densities. Early Hum Dev. 1988; 16 225-233
- 17 Appleton R E, Lee R EJ, Hey E N. Neurodevelopmental outcome of transient neonatal intracerebral echodensities. Arch Dis Child. 1990; 65 27-29
- 18 De Vries L S, Eken P, Dubowitz L MS. The spectrum of leukomalacia using cranial ultrasound. Behav Brain Res. 1992; 49 1-6
- 19 Leviton A, Gilles F. Ventriculomegaly, delayed myelination, white matter hypoplasia, and “periventricular” leukomalacia. How are they related?. Pediatr Neurol. 1996; 15 127-136
- 20 Sie L TL, van der Knaap M S, van Wezel-Meijler G et al.. Early MR features of hypoxic-ischemic brain injury in neonates with periventricular densities of sonograms. AJNR Am J Neuroradiol. 2000; 21 852-861
- 21 Olsen P, Vainionpaa L, Paakko E et al.. Psychological findings in preterm children related to neurological status and magnetic resonance imaging. Pediatrics. 1998; 102 329-336
- 22 Peterson B S, Vohr B, Staib L H et al.. Regional brain volume abnormalities and long-term cognitive outcome in preterm infants. JAMA. 2000; 284 1939-1947
- 23 Inder T E, Huppi P S, Warfield S et al.. Periventricular white matter injury in the premature infant is followed by reduced cerebral cortical gray matter volume at term. Ann Neurol. 1999; 46 755-760
- 24 Van de Bor M, Guit G L, Schreuder A M et al.. Does every preterm birth impair myelination of the central nervous system?. Neuropediatrics. 1990; 21 37-39
- 25 Guit G L, van der Bor M, den Ouden L, Wondergem J HM. Prediction of neurodevelopmental outcome in the preterm infant: MR-staged myelination compared with cranial US. Radiology. 1990; 175 107-109
- 26 Roelants-van Rijn A M, Nikkels P GJ, Groenendaal F et al.. Neonatal diffusion-weighted MR imaging: relation with histopathology or follow-up MR examination. Neuropediatrics. 2001; 32 286-294
- 27 Huppi P S, Murphy B, Maier S E et al.. Microstructural brain development after perinatal cerebral white matter injury assessed by diffusion tensor magnetic resonance imaging. Pediatrics. 2001; 107 455-460
- 28 Blankenberg F G, Loh N N, Norbash A M et al.. Impaired cerebrovascular autoregulation after hypoxic-ischemic injury in extremely low-birth-weight neonates: detection with power and pulsed wave Doppler US. Radiology. 1997; 205 563-568
- 29 Meek J H, Tyszczuk L, Elwell C E, Wyatt J S. Low cerebral blood flow is a risk factor for severe intraventricular haemorrhage. Arch Dis Child Fetal Neonatal Ed. 1999; 81 F15-F18
- 30 Borch K, Greisen G. Blood flow distribution in the normal human preterm brain. Pediatr Res. 1998; 43 28-33
- 31 Valkama A M, Ahonen A, Vainionpaa L, Torniainen P, Lanning P, Koivisto M. Brain single photon emission computed tomography at term age for predicting cerebral palsy after preterm birth. Biol Neonate. 2001; 79 27-33
- 32 Tatlisumak T. Is CT or MRI the method of choice for imaging patients with acute stroke? Why should men divide if fate has united?. Stroke. 2002; 33 2144-2145
Ivan L HandM.D.
Director of Neonatology, Department of Pediatrics, Room 803, Jacobi Medical Center
1400 Pelham Parkway, Bronx, NY 10461