Stereoselective Synthesis and Reactivity of Dienyl Zirconocene Derivatives

Abstract

Stereoselective dienyl zirconocene derivatives have been prepared via a tandem allylic C-H bond activation isomerization-elimination reaction. These reagents can be either trapped directly with electrophiles or transmetalated to copper to participate in several carbon-carbon bond formations. When the transmetalation is performed on allylic as well as vinylic zirconocene derivatives, the reaction occurs with inversion of stereochemistry of the dienyl system.

zirconocene - dienyls - transmetalation - isomerization

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