Abstract
(+)-Preussin was synthesized in ten steps with an overall yield of 6.4% from phenylacetaldehyde. The three stereogenic centers were controlled by enantioselective allyltitanations of aldehydes.
Key words
preussin - allyltitanation - cross-metathesis
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[3
Figure 3
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11 The formation of tetrahydrofuran B as secondary product could be observed during the cyclization process (Figure
[4
Figure 4
