Abstract
Sulphamic acid (H2 NSO3 H, SA) is used as an alternative to conventional acid catalysts in the Pechmann condensation of phenols with β-ketoester leading to the formation of substituted coumarin. The method is simple, cost-effective, solvent-free and gives good yields in a short reaction time.
Key words
sulphamic acid - Pechmann reaction - coumarins
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Typical Experimental Procedure: To the weighed quantity of phenol (10 mmol), and β-keto ester (10 mmol), the sulphamic acid (5 mmol) was added and the reaction mixture was stirred at 130 °C in a pre-heated oil-bath. After completion of the reaction at the desired time as indicated in Table
[1
