Abstract
2-Dibenzylamino-5-oxopentanoic acid benzyl ester has been obtained in good yields by complete benzylation of l -glutamic acid in NaOH and Na2 CO3 , selective reduction of the γ-ester into alcohol with DIBAL and further transformation into aldehyde using Swern oxidation. The overall three-step procedure from Glu gave aldehyde in 49% yield.
Key words
aldehydes - amino acids - reductions - oxidations - protecting groups
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