Bi(NO3)3·5H2O-TBAF as an Efficient Reagent for in situ Oxidation: Dihydropyrimidinone Formation from Benzyl Halides

Mohammad Mehdi Khodaei; Ahmad Reza Khosropour; Mahbubeh Jowkar

doi:10.1055/s-2005-861876

PAPER

Bi(NO₃)₃·5H₂O-TBAF as an Efficient Reagent for in situ Oxidation: Dihydropyrimidinone Formation from Benzyl Halides

Mohammad Mehdi Khodaei*, Ahmad Reza Khosropour*, Mahbubeh Jowkar
Department of Chemistry, Razi University, Kermanshah 67149, Iran
Fax: +98(831)4274559; e-Mail: mmkhoda@razi.ac.ir;

Abstract

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Abstract

The oxidation of benzyl halides to aldehydes with bismuth nitrate pentahydrate in an ionic liquid was studied. Also, an efficient one-pot synthesis of 3,4-dihydropyrimidin-2(1H)-ones from benzyl halides using bismuth nitrate pentahydrate in tetrabutylammonium fluoride (TBAF) as an in situ oxidant and catalyst is described.

Key words

dihydropyrimidinones - benzyl halides - oxidation-cyclocondensation - Bi(NO₃)₃·5H₂O-TBAF - ionic liquid

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