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Am J Perinatol 2005; 22(4): 173-179
DOI: 10.1055/s-2005-867087
Copyright © 2005 by Thieme Medical Publishers, Inc., 333 Seventh Avenue, New York, NY 10001, USA.

Improvement of Conventional Transcutaneous Bilirubinometry Results in Term Newborn Infants

Zlata Felc1
  • 1General Hospital, Neonatal Unit, Oblakova ulica 5, 3000 Celje, Slovenia
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Publication History

Publication Date:
02 May 2005 (online)

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ABSTRACT

This prospective study was performed to determine a way to improve conventional transcutaneous bilirubinometry results in healthy term newborn infants. In 118 infants during phototherapy (group A), and in 118 infants without phototherapy (group B), bilirubin determinations were done in duplicate using the Minolta AirShields Jaundice Meter type 101 (transcutaneous bilirubin index [TcB]), and the diazometric method on the Hitachi 717 Automated Analyzer (total reacting serum bilirubin [SeB]). In 112 infants (group C), bilirubin determinations were done in triplicate, using simple direct-reading photometry on the Moltronic Bilirubinometer (direct serum bilirubin [BiB]). A close correlation between TcB and SeB values was observed in group A (r = 0.69; p < 0.001) and in group B (r = 0.59; p < 0.001). The 95% confidence intervals of TcB readings corresponding to SeB were ± 80.7 μmol/L in group A and ± 76.9 μmol/L in group B, respectively. In group C, using a correctly calibrated BiB with adult sera containing bilirubin concentration in the range 271 to 344 μmol/L, the 95% confidence intervals of parallel TcB and BiB readings corresponding to SeB were ± 28 μmol/L. Parallel determinations of the TcB and the BiB in healthy term newborn infants give results almost identical to those of bilirubin determination by the laboratory method.

KEYWORDS

Transcutaneous bilirubinometry - conventional - term newborn infant

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Zlata FelcM.D. 

General Hospital, Neonatal Unit, Celje, Slovenia