Palladium-Catalyzed Suzuki-Miyaura Reactions of Potassium Aryl- and Heteroaryltrifluoroborates with Aryl- and Heteroaryl Triflates

Gary A. Molander; Daniel E. Petrillo; Nicole R. Landzberg; John C. Rohanna; Betina Biolatto

doi:10.1055/s-2005-871544

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Palladium-Catalyzed Suzuki-Miyaura Reactions of Potassium Aryl- and Heteroaryltrifluoroborates with Aryl- and Heteroaryl Triflates

Gary A. Molander*, Daniel E. Petrillo, Nicole R. Landzberg, John C. Rohanna, Betina Biolatto
Roy and Diana Vagelos Laboratories, Department of Chemistry, University of Pennsylvania, Philadelphia, Pennsylvania 19104-6323, USA
Fax: +1(215)5737165; e-Mail: gmolandr@sas.upenn.edu;

Abstract

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Abstract

The Suzuki-Miyaura cross-coupling of potassium aryl- and heteroaryltrifluoroborates with aryl- and heteroaryl triflates is reported. The catalyst system provides good to excellent yields using sterically hindered and electronically diverse coupling partners.

Key words

Suzuki-Miyaura - palladium - cross-coupling - biaryls - aryltrifluoroborates - aryl triflates

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