Semin Thromb Hemost 2005; 31(3): 302-306
DOI: 10.1055/s-2005-872436
Copyright © 2005 by Thieme Medical Publishers, Inc., 333 Seventh Avenue, New York, NY 10001, USA.

The Egogram Is a Potent, Independent Risk Factor for Hypertension in Pregnancy

Gen Kobashi1 , 2 , Kaori Ohta2 , 3 , Koichi Shido2 , Akira Hata4 , Hideto Yamada3 , Hisanori Minakami3 , Hiko Tamashiro2 , Seiichiro Fujimoto3 , Kiyotaro Kondo5
  • 1Assistant Professor, Hokkaido University School of Medicine, Sapporo, Japan
  • 2Division of Preventive Medicine, Hokkaido University School of Medicine, Sapporo, Japan
  • 3Department of Obstetrics and Gynecology, Hokkaido University School of Medicine, Sapporo, Japan
  • 4Department of Public Health, Asahikawa Medical College School of Medicine, Asahikawa, Japan
  • 5The University of the Air, Chiba, Japan
Further Information

Publication History

Publication Date:
28 July 2005 (online)

ABSTRACT

To assess the association between the egogram and hypertension in pregnancy (HP), a case-control study was carried out. Seventy-one HP cases, primiparous aged 20 to 34 years, and 109 controls, were enrolled among pregnant women who visited our hospitals for obstetrical care. Data from a self-administered questionnaire containing a Self Grow-Up Egogram (SGE) were subjected to univariate and multivariate analyses with prepregnancy body mass index (BMI) and angiotensinogen (AGT) genotype. The mean ± standard error of total scores for the critical parent (CP) scale were 9.7 ± 0.5 for cases and 8.3 ± 0.3 for controls, those for the nurturing parent (NP) scale were 13.6 ± 0.4 for cases and 13.4 ± 0.3 for controls, those for the adult (A) scale were 11.3 ± 0.5 for cases and 10.9 ± 0.3 for controls, those for the free child (FC) scale were 12.3 ± 0.3 for cases and 13.8 ± 0.3 for controls, and those for the adapted child (AC) scale were 10.2 ± 0.4 for cases and 8.5 ± 0.4 for controls. A low FC scale score (FC ≤ 10) and a high AC scale score (AC > 10) were significantly associated with HP (p < 0.05; p < 0.01, respectively). In the multivariate analysis, FC ≤ 10, AC > 10, prepregnancy BMI ≥ 24, and homozygosity of the T235 allele genotype of the AGT gene were detected as the potent independent risk factors for HP. The odds ratios were 2.2, 2.8, 4.0, and 2.5, respectively. The present results suggest that a low FC score and a high AC score may be potent, independent risk factors for HP.

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 Dr.
Gen Kobashi

Professor, Division of Preventive Medicine, Hokkaido University Graduate School of Medicine

N15 W7, Sapporo 060-8638, Japan

Email: genkoba@med.hokudai.ac.jp