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Synthesis 2006(2): 366-367  
DOI: 10.1055/s-2005-918497
PSP
© Georg Thieme Verlag Stuttgart · New York

Large-Scale One-Pot Synthesis of N-Heterocyclic Carbene-Pd(allyl)Cl Complexes

Oscar Navarro, Steven P. Nolan*
Department of Chemistry, University of New Orleans, New Orleans, LA 70148, USA
Fax: +1(504)2806860; e-Mail: snolan@uno.edu;
Further Information

Publication History

Received 26 September 2005
Publication Date:
21 December 2005 (online)

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Abstract

Improved one-pot syntheses of (IPr)Pd(allyl)Cl {IPr = [N,N′-bis(2,6-diisopropylphenyl)imidazol]-2-ylidene} and (SIPr)Pd(allyl)Cl {SIPr = [N,N′-bis(2,6-diisopropylphenyl)-4,5-dihydroimidazol]-2-ylidene} complexes are described. This simple method utilizes technical grade isopropanol and water as solvents, affording gram quantities of the cross-coupling pre-catalysts.

Key words

N-heterocyclic carbene - palladium - homogeneous catalysis

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