DMW - Deutsche Medizinische Wochenschrift, Table of Contents Dtsch Med Wochenschr 2006; 131(16): 884-887DOI: 10.1055/s-2006-939863 Prinzip & Perspektive | Review article Regenerative Medizin, Kardiologie © Georg Thieme Verlag KG Stuttgart · New York Atriales Remodeling und Anti-Remodeling-Therapie bei Vorhofflimmern Atrial remodeling and anti-remodeling therapy in atrial fibrillationT. Neumann1 , H. Hölschermann2 1Medizinische Klinik I, Kardiologie und Angiologie, Universitätsklinikum Gießen und Marburg 2Medizinische Klinik I, Kardiologie und Angiologie, Hochtaunus-Kliniken Bad Homburg Recommend Article Abstract Buy Article Schlüsselwörter Atriales Remodeling - Anti-Remodeling-Therapie - Vorhofflimmern Key words atrial remodeling - anti-remodeling therapy - atrial fibrillation Full Text References Literatur 1 Ausma J, Wijfells M, Thone F. et al . Structural changes of atrial myocardium due to sustained atrial fibrillation in the goat. Circulation. 1997; 96 3157-3163 2 Corley S D, Epstein A E, DiMarco J P. et al . Relationships between sinus rhythm, treatment, and survival in the Atrial Fibrillation Follow-UP Investigation of Rhythm Management (AFFIRM) study. Circulation. 2004; 109 1509-1513 3 Ehrlich J R, Cha T J, Zhang L. et al . Characterization of a hyperpolarization-activated time-dependent potassium current in canine cardiomyocytes from pulmonary vein myocardial sleeves and left atrium. J Physiol. 2004; 557 583-597 4 Frustaci A, Chimenti C, Bellocci F. et al . Histological substrate of atrial biopsies in patients with lone atrial fibrillation. Circulation. 1997; 96 1180-1184 5 Fuster V, Rydèn L E, Asinger R W. et al . Guidelines for the management of patients with atrial fibrillation: executive summary. Circulation. 2001; 104 2118-2150 6 Goette A, Arndt M, Rocken C. et al . Regulation of angiotensin II receptor subtypes during atrial fibrillation in humans. Circulation. 2000; 101 2678-2681 7 Goldstein R N, Stambler B S. New antiarrhythmic drugs for prevention of atrial fibrillation. Progress in Cardiovascular diseases. 2005; 48 193-208 8 Hanna N, Cardin S, Leung T K. et al . Differences in atrial versus ventricular remodelling in dogs with ventricular tachypacing-induced congestive heart failure. Cardiovasc Res. 2004; 63 236-244 9 Lopez B, Querejeta R, Varo N. et al . Usefulness of serum carboxy-terminal propeptide of procollagen type I in assessment of the cardioreparative ability of antihypertensive treatment in hypertensive patients. Circulation. 2001; 104 286-291 10 Madrid A H, Peng J, Zamora J. et al . The role of angiotensin receptor blockers and/or angiotensin converting enzyme inhibitors in the prevention of atrial fibrillation in patients with cardiovascular diseases: meta-analysis of randomized controlled clinical trials. PACE. 2004; 27 1405-1410 11 Milliez P, DeAngelis N, Rucker-Martin C. et al . Spironolactone reduces fibrosis of dilated atria during heart failure in rats with myocardial infarction. European Heart Journal. 2005; 26 2193-2199 12 Morillo C A, Klein G J, Jones D L. et al . Chronic rapid atrial pacing. Structural, functional, and electrophysiological characteristics of a new model of sustained atrial fibrillation. Circulation. 1995; 91 1588-1595 13 Nakamura Y, Nakamura K, Fukushima-Kusano K. et al . Tissue factor expression in atrial endothelia associated with nonvalvular atrial fibrillation: possible involvement in intracardiac thrombogenesis. Thromb Res. 2003; 111 137-142 14 Nattel S. New ideas about atrial fibrillation 50 years on. Nature. 2002; 415 219-226 15 Reant P, Lafitte S, Jais P. et al . Reverse remodeling of the left cardiac chambers after catheter ablation after 1 year in a series of patients with isolated atrial fibrillation. Circulation. 2005; 112 2896-2903 16 Schotten U, Duytschaever M, Ausma J. et al . Electrical and contractile remodeling during the first days of atrial fibrillation go hand in hand. Circulation. 2003; 107 1433-1439 17 Shinagawa K, Shiroshita-Takeshita A, Schram G, Nattel S. Effects of antiarrhythmic drugs on fibrillation in the remodeled atrium. Circulation. 2003; 107 1440-1446 18 Tsao H M, Wu M H, Huang B H. et al . Morphologic remodeling of the pulmonary veins and left atrium after catheter ablation of atrial fibrillation: insights from long-term follow-up of three-dimensional magnetic resonance imaging. J Cardiovasc Electrophysiol. 2005; 16 7-12 19 Wetzel U, Boldt A, Lauschke J. et al . Expression of connexins 40 and 43 in human left atrium in atrial fibrillation in different aetiologies. Heart. 2005; 91 166-170 20 Yue L, Feng J, Gaspo R. et al . Ionic remodeling underlying action potential changes in a canine model of atrial fibrillation. Circ Res. 1997; 81 512-525 Priv.-Doz. Dr. Hans Hölschermann Medizinische Klinik I - Kardiologie und Angiologie, Hochtaunus-Kliniken Bad Homburg Urseler Str. 33 61348 Bad Homburg Phone: 06172-143132 Fax: 06172-144915 Email: hans.hoelschermann@hochtaunus-kliniken.de