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DOI: 10.1055/s-2006-940145
Subjektive Lebensqualität von Patienten mit Zwangserkrankungen im Vergleich mit der Allgemeinbevölkerung
Subjective Quality of Life of Patients with Obsessive-Compulsive Disorder Compared to the General PopulationPublikationsverlauf
Publikationsdatum:
05. Oktober 2006 (online)
Zusammenfassung
Hintergrund: Patienten mit Zwangserkrankungen sind in ihrer sozialen Funktionsfähigkeit eingeschränkt. In der vorliegenden Studie wurde die subjektive Lebensqualität dieser Patienten untersucht und mit der der Allgemeinbevölkerung verglichen. Methoden: Von 75 Patienten mit einer Zwangserkrankung (ICD-10 F42.0 - F42.2) ohne psychiatrische Komorbidität wurde die subjektive Lebensqualität mithilfe des WHOQOL-BREF erhoben. Ergebnisse: Verglichen mit der Allgemeinbevölkerung haben Patienten mit Zwangserkrankungen eine geringere Lebensqualität. Schlussfolgerung: Interventionen, die das psychosoziale Funktionsniveau erhöhen, sollten in die Behandlung von Patienten mit Zwangserkrankungen verstärkt integriert werden.
Abstract
Background: Patients with obsessive-compulsive disorder (OCD) not only suffer from obsessive-compulsive symptoms, but also the disorder is associated with impaired social functioning, which impact their everyday life negatively. Objective: Subjective quality of life (QoL) in patients with OCD was examined and compared to the general German population. Methods: 75 patients with OCD (ICD-10 F42.0 - F42.2) were recruited from the outpatient clinic for anxiety disorders at the Department of Psychiatry of the University of Leipzig. Patients showing psychiatric co-morbidity were excluded. By means of the WHOQOL-BREF, QoL was assessed in patients with OCD and in a sample of the general population of Saxony/Germany. Results: Compared with the general population, QoL in patients with obsessive-compulsive disorders was lower in all domains of the WHOQOL-BREF. Conclusion: OCD has a substantial adverse effect on patients' subjective QoL. Therefore, it will be necessary to include interventions in the treatment of OCD aimed at improving residual deficits in psychosocial functioning and QoL.
Literatur
- 1 Bebbington P E. Epidemiology of obsessive-compulsive disorder. Br J Psychiatry. 1998; 35 2-6
- 2 Denys D, Tenney N, Megen H J van, Geus F de, Westenberg H G. Axis I and II comorbidity in a large sample of patients with obsessive-compulsive disorder. J Affect Disord. 2004 a; 80 155-162
- 3 Hollander E, Zohar J. Beyond refractory obsessions and anxiety states: toward remission. J Clin Psychiatry. 2004; 65 3-5
- 4 Grabe H J, Meyer C, Hapke U, Rumpf H J, Freyberger H J, Dilling H, John U. Prevalence, quality of life and psychosocial function in obsessive-compulsive disorder and subclinical obsessive-compulsive disorder in northern Germany. Eur Arch Psychiatry Clin Neurosci. 2000; 250 262-268
- 5 Stengler-Wenzke K, Angermeyer M C. Inanspruchnahme von professioneller Hilfe von Patienten mit Zwangserkrankungen. Psychiat Prax. 2005; 32 195-201
- 6 Fineberg N A, O'Doherty C, Rajagopal S, Reddy K, Banks A, Gale T M. How common is obsessive-compulsive disorder in a dermatology outpatient clinic?. J Clin Psychiatry. 2003; 64 152-155
- 7 Greist J H, Bandelow B, Hollander E, Marazziti D, Montgomery S A, Nutt D J, Okasha A, Swinson R P, Zohar J. World Council of Anxiety. WCA recommendations for the long-term treatment of obsessive-compulsive disorder in adults. CNS Spectr. 2003; 8 7-16
- 8 Koran L M, Thienemann M L, Davenport R. Quality of life for patients with obsessive-compulsive disorder. Am J Psychiatry. 1996; 153 738
- 9 Hollander E, Kwon J H, Stein D J, Broatch J, Rowland C T, Himelein C A. Obsessive-compulsive and spectrum disorders: overview and quality of life issues. J Clin Psychiatry. 1996; 57 3-6
- 10 Bystritsky A, Liberman R P, Hwang S, Wallace C J, Vapnik T, Maindment K, Saxena S. Social functioning and quality of life comparisons between obsessive-compulsive and schizophrenic disorders. Depress Anxiety. 2001; 14 214-218
- 11 Lochner C, Mogotsi M, Toit P L du, Kaminer D, Niehaus D J, Stein D J. Quality of life in anxiety disorders: A comparison of obsessive-compulsive disorder, social anxiety disorder, and panic disorder. Psychopathology. 2003; 36 255-260
- 12 Masellis M, Rector N A, Richter M A. Quality of life in OCD: differential impact of obsessions, compulsions, and depression comorbidity. Can J Psychiatry. 2003; 48 72-77
- 13 Moritz S, Rufer M, Fricke S, Karow A, Morfeld M, Jelinek L, Jacobsen D. Quality of life in obsessive-compulsive disorder before and after treatment. Compr Psychiatry. 2005; 46 453-459
- 14 Rapaport M H, Clary C, Fayyad R, Endicott J. Quality-of-life impairment in depressive and anxiety disorders. Am J Psychiatry. 2005; 162 1171-1178
- 15 Eisen J L, Mancebo M A, Pinto A, Coles M E, Pagano M E, Stout R, Rasmussen S A. Impact of obsessive-compulsive disorder on quality of life. Compr Psychiatry. 2006; 47 270-275
- 16 World Health Organization .The 10th revision of the International Classification of Diseases. Chapter V (F): Mental and Behavioral Disorders. Göttingen; Huber 1993
- 17 Goodman W K, Price L H, Rasmussen S A, Mazure C, Fleischmann R L, Hill C L, Heninger G R, Charney D S. The Yale-Brown Obsessive Compulsive Scale. I. Development, use, and reliability. Arch Gen Psychiatry. 1989a; 46 1006-1011
- 18 Goodman W K, Price L H, Rasmussen S A, Mazure C, Delgado P, Heninger G R, Charney D S. The Yale-Brown Obsessive Compulsive Scale. II. Validity. Arch Gen Psychiatry. 1989 b; 46 1012-1016
- 19 Deacon B J, Abramowitz J S. The Yale-Brown Obsessive Compulsive Scale: factor analysis, construct validity, and suggestions for refinement. J Anxiety Disord. 2005; 19 573-585
- 20 Angermeyer M C, Kilian R, Matschinger H. WHOQOL-100 und WHOQOL-BREF. Göttingen; Hogrefe 2000
- 21 Steketee G. Disability and family burden in obsessive-compulsive disorder. Can J Psychiatry. 1997; 42 919-928
- 22 Bobes J, Gonzalez M P, Bascaran M T, Arango C, Saiz P A, Bousono M. Quality of life and disability in patients with obsessive-compulsive disorder. Eur Psychiatry. 2001; 16 239-245
Dr. med. Katarina Stengler-Wenzke
Klinik und Poliklinik für Psychiatrie · Universität Leipzig
Johannisallee 20
04317 Leipzig
eMail: stenglk@medizin.uni-leipzig.de