Subscribe to RSS
DOI: 10.1055/s-2006-947183
Acute Delusional Parasitosis under Treatment with Ciprofloxacin
A Case ReportPublication History
Received: 13.1.2006
Revised: 13.4.2006
Accepted: 8.5.2006
Publication Date:
27 July 2006 (online)
Ciprofloxacin-induced psychoses have been described in some case reports, occurring sometimes in multi-morbid or personality disordered patients, but also in healthy subjects. We present a case of a 45-year-old man without previous mental disorder, who developed an acute delusional parasitosis after administration of ciprofloxacin. After discontinuation of ciprofloxacin, a complete and sustained remission could be observed within a few days, without the use of any psychopharmacologic medication. Possible modes of action are discussed.
References
- 1 Abouesh A, Stone C, Hobbs W R. Antimicrobial-induced mania (anitbiomania): a review of spontaneous reports. J Clin Psychopharmacol. 2002; 22 71-81
- 2 Galatti L, Giustini E, Sessa A, Polimeni G, Solvo F, Spina E. Neuropsychiatric adverse drug reactions in general practice. Pharmacopsychiatry. 2005; 38 41-68
-
3 Grimm O, Alm B. A case of ciprofloxacin-induced acute polymorphic psychosis with a distinct deficit of the executive functions. Unpublished preprint 2006; http://cogprints.org/4187/.
- 4 Hollweg M, Kapfhammer H P, Krupinski M, Möller H J. Psychopathologische Syndrome unter Behandlung mit Gyrasehemmern. Nervenarzt. 1997; 68 38-47
- 5 Jüngst G, Mohr R. Side effects of ofloxacin in clinical trials in postmarketing surveillance. Drugs. 1987; 34 (Suppl 1) 144-149
- 6 Mc Cue J D, Zandt J R. Acute psychoses associated with the use of ciprofloxacin and trimethoprim-sulfamethoxazole. Ann J Med. 1991; 90 528-529
- 7 Mulhall J P, Bergmann L S. Ciprofloxacin-induced acute psychosis. Urology. 1995; 46 102-103
- 8 Reeves R R. Ciprofloxacin induced psychosis. Ann Phamacother. 1992; 26 930-931
- 9 Rothenhäusler H B, Grieser B, Nollert G, Reichart B, Schelling G, Kapfhammer H P. Psychiatric and psychosocial outcome of cardiac surgery with cardiopulmonary bypass: a prospective 12-month follow-up study. Gen Hosp Psychiatry. 2005; 27 18-28
- 10 Trabert W. 100 years of delusional parasitosis. Meta-analysis of 1223 case reports. Psychopathology. 1995; 28 238-246
- 11 Tripathi A, Chen S I, O’ Sullivan S. Acute psychosis following the use of topical ciprofloxacin. Arch Ophthalmol. 2002; 120 665-666
- 12 Tsuji A, Sato H, Kume Y. Inhibitory effects of quinolone antibacterial agents on aminobutyric acid binding to receptor sites in rat brain membrane. Antimicrob Agents Chemother. 1988; 32 190-194
Prof. Dr. med. Tilman Steinert
Center for Psychiatry Weissenau
University of Ulm
Weingartshofer Straße 2
88214 Ravensburg-Weissenau
Phone: +49 751 7601 2738
Fax: +49 751 7601 2706
Email: tilman.steinert@zfp-weissenau.de