Extended-Donor Criteria Liver Allografts

Barbara Alkofer; Benjamin Samstein; James V. Guarrera; Cindy Kin; Dominique Jan; Sarah Bellemare; Milan Kinkhabwala; Robert Brown; Jean C. Emond; John F. Renz

doi:10.1055/s-2006-947292

Seminars in Liver Disease, Table of Contents

Semin Liver Dis 2006; 26(3): 221-233
DOI: 10.1055/s-2006-947292

Extended-Donor Criteria Liver Allografts

Barbara Alkofer¹ , Benjamin Samstein¹ , James V. Guarrera¹ , Cindy Kin¹ , Dominique Jan¹ , Sarah Bellemare¹ , Milan Kinkhabwala¹ , Robert Brown¹ Jr. , Jean C. Emond¹ , John F. Renz¹

¹Center for Liver Disease and Transplantation, New York-Presbyterian Hospital, New York, New York

Abstract

ABSTRACT

Extended-donor criteria liver allografts do not meet traditional criteria for transplantation. Although these organs offer immediate expansion of the donor pool, transplantation of extended-donor criteria liver allografts increases potential short- and long-term risk to the recipient. This risk may manifest as impaired allograft function or donor-transmitted disease. Guidelines defining this category of donor, level of acceptable risk, principles of consent, and post-transplantation surveillance have not been defined. This article reviews the utilization, ethical considerations, and outcomes of extended-donor criteria liver allografts.

KEYWORDS

Liver transplantation - extended-donor criteria

Full Text

References

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John F RenzM.D. Ph.D.

Center for Liver Disease and Transplantation, New York-Presbyterian Hospital

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