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Semin Liver Dis 2006; 26(3): 221-233
DOI: 10.1055/s-2006-947292
Copyright © 2006 by Thieme Medical Publishers, Inc., 333 Seventh Avenue, New York, NY 10001, USA.

Extended-Donor Criteria Liver Allografts

Barbara Alkofer1 , Benjamin Samstein1 , James V. Guarrera1 , Cindy Kin1 , Dominique Jan1 , Sarah Bellemare1 , Milan Kinkhabwala1 , Robert Brown1  Jr. , Jean C. Emond1 , John F. Renz1
  • 1Center for Liver Disease and Transplantation, New York-Presbyterian Hospital, New York, New York
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Publication History

Publication Date:
19 July 2006 (online)

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ABSTRACT

Extended-donor criteria liver allografts do not meet traditional criteria for transplantation. Although these organs offer immediate expansion of the donor pool, transplantation of extended-donor criteria liver allografts increases potential short- and long-term risk to the recipient. This risk may manifest as impaired allograft function or donor-transmitted disease. Guidelines defining this category of donor, level of acceptable risk, principles of consent, and post-transplantation surveillance have not been defined. This article reviews the utilization, ethical considerations, and outcomes of extended-donor criteria liver allografts.

KEYWORDS

Liver transplantation - extended-donor criteria

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John F RenzM.D. Ph.D. 

Center for Liver Disease and Transplantation, New York-Presbyterian Hospital

622 West 168th Street, Room PH-14C, New York, NY 10032