Am J Perinatol 2008; 25(2): 101-103
DOI: 10.1055/s-2007-1004833
© Thieme Medical Publishers

Intractable Respiratory Failure in a Term Newborn

Lisa Allred1 , Robert Ruiz2 , Donna Jones2 , Steven M. Donn1
  • 1Division of Neonatal-Perinatal Medicine, Department of Pediatrics, C.S. Mott Children's Hospital, University of Michigan Health System, Ann Arbor, Michigan
  • 2Department of Pathology, C.S. Mott Children's Hospital, University of Michigan Health System, Ann Arbor, Michigan
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Publikationsverlauf

Publikationsdatum:
31. Dezember 2007 (online)

ABSTRACT

Birth depression unresponsive to conventional resuscitative measures merits careful consideration. The case of a term infant with primary respiratory failure at birth despite extensive intervention is presented. Postmortem examination revealed bilateral pulmonary artery thrombi, which underscores the importance of careful exploration of possible pathogenetic mechanisms.

REFERENCES

  • 1 Abrantes M, Lacerda A F, Abreu C R, Levy A, Azevedo A, Da S L. Cerebral venous sinus thrombosis in a neonate due to factor V Leiden deficiency.  Acta Paediatr. 2002;  91 243-245
  • 2 Mettey R, Rosolacci M N, Gagnadoux M F et al.. Neonatal venous thrombosis and familial protein C deficiency. A difficult diagnosis.  Ann Pediatr (Paris). 1989;  36(5) 343-344
  • 3 Rogers P C, Silva M P, Carter J E, Wadsworth L D. Renal vein thrombosis and response to therapy in a newborn due to protein C deficiency.  Eur J Pediatr. 1989;  149(2) 124-125
  • 4 Tardy-Poncet B, Rayet I, Damon G, Alhenc-Gelas M, Dutour N, Lavocat M P. Protein C concentrates in a neonate with a cerebral venous thrombosis due to heterozygous type 1 protein C deficiency.  Thromb Haemost. 2001;  85(6) 1118-1119
  • 5 Gould R J, Black K, Pavlakis S G. Neonatal cerebral arterial thrombosis: Protein C deficiency.  J Child Neurol. 1996;  11(3) 250-252
  • 6 Roman K, Rosenthal E, Razavi R. Pulmonary arterial thrombosis in a neonate with homozygous deficiency of antithrombin III: Successful outcome following pulmonary thrombectomy and infusions of antithrombin III concentrate.  Cardiol Young. 2000;  10(3) 275-278
  • 7 Sanchez J, Velasco F, Alvarez R, Roman J, Torres A. Aortic thrombosis in a neonate with hereditary antithrombin III deficiency: Successful outcome with thrombolytic and replacement treatment.  Acta Paediatr. 1996;  85(2) 245-247
  • 8 Hoppe C, Matsunaga A. Pediatric thrombosis.  Pediatr Clin North Am. 2002;  49 1257-1283
  • 9 Goble M M, Gomez C A. Neonatal pulmonary artery thrombosis: Echocardiographic characteristics and possible contributing factors.  J Am Soc Echocardiogr. 2005;  18 693

Lisa AllredM.D. 

F5790 Mott Hospital, 1500 E. Medical Center Drive

Ann Arbor, MI 48109-0254

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