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TumorDiagnostik & Therapie 2007; 28(3): 129-132
DOI: 10.1055/s-2007-963252
DOI: 10.1055/s-2007-963252
Thieme Onkologie aktuell
© Georg Thieme Verlag KG Stuttgart · New York
Gentherapeutische Strategien gegen das kolorektale Karzinom
Gene therapy approaches for colorectal cancerFurther Information
Publication History
eingereicht: 19.10.2006
angenommen: 8.2.2007
Publication Date:
15 June 2007 (online)
Schlüsselwörter
Gentherapie - kolorektales Karzinom - Immuntherapie - Stammzelltherapie
Key words
Gene therapy - colorectal cancer - immune therapy - stem cell therapy
Literatur
- 1 Weitz J, Koch M, Debus J, Hohler T, Galle P R, Buchler M W. Colorectal cancer. Lancet. 2005; 365 153-365
- 2 Venook A. Critical evaluation of current treatments in metastatic colorectal cancer. Oncologist. 2005; 10 250-261
- 3 Zwacka R M, Dunlop M G. Gene therapy for colon cancer. Hematol Oncol Clin North Am. 1998; 12 595-615
- 4 Cross D, Burmester J K. Gene therapy for cancer treatment: past, present and future. Clin Med Res. 2006; 4 218-227
- 5 Bischoff J R, Kirn D H, Williams A. et al . An adenovirus mutant that replicates selectively in p53-deficient human tumor cells. Science. 1996; 274 373-376
- 6 Li C, Bowles D E, Dyke van T, Samulski R J. Adeno-associated virus vectors: potential applications for cancer gene therapy. Cancer Gene Ther. 2005; 12 913-925
- 7 Mohr A, Henderson G, Dudus L, Herr I, Kuerschner T, Debatin K M, Weiher H, Fisher K J, Zwacka R M. AAV-encoded expression of TRAIL in experimental human colorectal cancer leads to tumor regression. Gene Ther. 2004; 11 534-543
- 8 Glick R P, Lichtor T, Cohen E P. Cytokine immunogene therapy. Neurosurg Focus. 2000; 9 e2
- 9 Morgan R A, Dudley M E, Wunderlich J R. et al . Cancer regression in patients after transfer of genetically engineered lymphocytes. Science. 2006; 314 126-129
- 10 Studeny M, Marini F C, Champlin R E, Zompetta C, Fidler I J, Andreeff M. Bone marrow-derived mesenchymal stem cells as vehicles for interferon-beta delivery into tumors. Cancer Res. 2002; 62 3603-3608
Dr. Ralf Zwacka
Universität Ulm
Sektion Gentherapie
Helmholtzstraße 8/1
89081 Ulm
Phone: ++ 49-731-500 33617
Fax: ++ 49-731-500 33609
Email: ralf.zwacka@uni-ulm.de