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Synthesis 2007(5): 705-708
DOI: 10.1055/s-2007-965904
DOI: 10.1055/s-2007-965904
PAPER
© Georg Thieme Verlag Stuttgart · New York
Stereoselective Synthesis of a Mevinic Acid Analogue [1]
Further Information
Publication History
Received
24 October 2006
Publication Date:
25 January 2007 (online)


Abstract
An efficient and versatile synthetic method for the stereoselective synthesis of a mevinic acid analogue is described. This approach uses a combination of a Cosford protocol with a catecholborane-mediated stereoselective reduction of acyclic β-hydroxy ketones to syn-1,3-diols, as key steps.
Key words
mevinic acid analogue - Cosford protocol - β-hydroxy ketones - catecholborane - syn-1,3-diols
IICT Communication No: 060910.